Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3940866..3941526 Replicon chromosome
Accession NZ_OW968328
Organism Enterobacter cloacae isolate 1382

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag LQ108_RS18705 Protein ID WP_230136681.1
Coordinates 3940866..3941279 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A5E1AG01
Locus tag LQ108_RS18710 Protein ID WP_013098615.1
Coordinates 3941260..3941526 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ108_RS18685 (AI2999V1_3631) 3936859..3938592 - 1734 WP_108453881.1 single-stranded-DNA-specific exonuclease RecJ -
LQ108_RS18690 (AI2999V1_3632) 3938598..3939311 - 714 WP_013098611.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
LQ108_RS18695 (AI2999V1_3633) 3939340..3940236 - 897 WP_013098612.1 site-specific tyrosine recombinase XerD -
LQ108_RS18700 (AI2999V1_3634) 3940338..3940859 + 522 WP_013098613.1 flavodoxin FldB -
LQ108_RS18705 (AI2999V1_3635) 3940866..3941279 - 414 WP_230136681.1 protein YgfX Toxin
LQ108_RS18710 (AI2999V1_3636) 3941260..3941526 - 267 WP_013098615.1 FAD assembly factor SdhE Antitoxin
LQ108_RS18715 (AI2999V1_3637) 3941821..3942801 + 981 WP_023620448.1 tRNA-modifying protein YgfZ -
LQ108_RS18720 (AI2999V1_3638) 3942911..3943570 - 660 WP_003863433.1 hemolysin III family protein -
LQ108_RS18725 (AI2999V1_3640) 3943836..3944567 + 732 WP_020687085.1 MurR/RpiR family transcriptional regulator -
LQ108_RS18730 (AI2999V1_3641) 3944684..3946117 + 1434 WP_230136683.1 6-phospho-beta-glucosidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16278.21 Da        Isoelectric Point: 10.1988

>T296099 WP_230136681.1 NZ_OW968328:c3941279-3940866 [Enterobacter cloacae]
VVLWQSDLRVSWRSQWMSLLLHGLVAAFVLLMPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGQ
EWDILGMPWMLSSGMMLRLRQVDGGKCQHLWLAADSMDIAEWRELRRMLLQQQPTQE

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10569.05 Da        Isoelectric Point: 5.1456

>AT296099 WP_013098615.1 NZ_OW968328:c3941526-3941260 [Enterobacter cloacae]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDEDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A5E1AG01

References