Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 1323297..1324069 Replicon chromosome
Accession NZ_OW968280
Organism Klebsiella oxytoca isolate 101

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag LQ191_RS06375 Protein ID WP_032938032.1
Coordinates 1323297..1323671 (-) Length 125 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag LQ191_RS06380 Protein ID WP_049101822.1
Coordinates 1323710..1324069 (-) Length 120 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ191_RS06350 (AI2946V1_1241) 1318979..1319212 - 234 WP_004132711.1 hypothetical protein -
LQ191_RS06355 1319612..1319884 + 273 WP_016247220.1 hypothetical protein -
LQ191_RS06360 (AI2946V1_1243) 1320087..1320995 + 909 WP_032938037.1 kdo(2)-lipid IV(A) palmitoleoyltransferase -
LQ191_RS06365 (AI2946V1_1244) 1321769..1322758 + 990 WP_047058004.1 glycosyltransferase -
LQ191_RS06370 (AI2946V1_1245) 1322762..1323217 + 456 WP_223226960.1 hypothetical protein -
LQ191_RS06375 (AI2946V1_1247) 1323297..1323671 - 375 WP_032938032.1 TA system toxin CbtA family protein Toxin
LQ191_RS06380 (AI2946V1_1248) 1323710..1324069 - 360 WP_049101822.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
LQ191_RS06385 (AI2946V1_1249) 1324092..1324313 - 222 WP_032938028.1 DUF987 domain-containing protein -
LQ191_RS06390 (AI2946V1_1250) 1324327..1324809 - 483 WP_032938026.1 DNA repair protein RadC -
LQ191_RS06395 (AI2946V1_1252) 1325050..1325529 - 480 WP_075206252.1 antirestriction protein -
LQ191_RS06400 (AI2946V1_1253) 1325609..1326430 - 822 WP_071067384.1 DUF932 domain-containing protein -
LQ191_RS06405 (AI2946V1_1254) 1326541..1326753 - 213 WP_032938024.1 hypothetical protein -
LQ191_RS06410 (AI2946V1_1255) 1326863..1327336 - 474 WP_189095326.1 hypothetical protein -
LQ191_RS06415 (AI2946V1_1256) 1327410..1328039 - 630 WP_032938019.1 hypothetical protein -
LQ191_RS06420 (AI2946V1_1257) 1328137..1328814 - 678 WP_032938016.1 WYL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1320087..1346072 25985


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(9-112)

Antitoxin

Antitoxin CbeA

(15-114)


Sequences

Toxin        


Download         Length: 125 a.a.        Molecular weight: 13903.92 Da        Isoelectric Point: 9.7700

>T296050 WP_032938032.1 NZ_OW968280:c1323671-1323297 [Klebsiella oxytoca]
MQIQSLPPQRAASSRLSSVKIWQKLLEYLLEQHYGLTLNDTPFGNDSVIQKHIDAGISLCDAVNFIVEKYDLVRTDRHGF
SVKEQSPFIGSLDMLRDRKATGLMTRKGYKTVTDITGGRFSGGK

Download         Length: 375 bp

Antitoxin


Download         Length: 120 a.a.        Molecular weight: 13393.59 Da        Isoelectric Point: 8.8636

>AT296050 WP_049101822.1 NZ_OW968280:c1324069-1323710 [Klebsiella oxytoca]
MQKATRVINHNIAEPWWGLRRNVTPCFGARLVQEGNRLHYLADRASTTGTFNDADLRHLDQAFPLLMKQMELMLTSSELM
PRIQRCITLHAKGLICKADTLGSCGYLYIVIYPASATTA

Download         Length: 360 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References