Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 864797..865454 Replicon chromosome
Accession NZ_OW968280
Organism Klebsiella oxytoca isolate 101

Toxin (Protein)


Gene name cptA Uniprot ID A0A181X6I0
Locus tag LQ191_RS04165 Protein ID WP_004105559.1
Coordinates 865044..865454 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A285B945
Locus tag LQ191_RS04160 Protein ID WP_004105561.1
Coordinates 864797..865063 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ191_RS04135 (AI2946V1_0809) 859976..861409 - 1434 WP_126489546.1 6-phospho-beta-glucosidase -
LQ191_RS04140 (AI2946V1_0810) 861530..862258 - 729 WP_064352017.1 MurR/RpiR family transcriptional regulator -
LQ191_RS04145 (AI2946V1_0811) 862309..862620 + 312 WP_126489545.1 N(4)-acetylcytidine aminohydrolase -
LQ191_RS04150 (AI2946V1_0812) 862782..863441 + 660 WP_064344096.1 hemolysin III family protein -
LQ191_RS04155 (AI2946V1_0813) 863570..864553 - 984 WP_004115279.1 tRNA-modifying protein YgfZ -
LQ191_RS04160 (AI2946V1_0815) 864797..865063 + 267 WP_004105561.1 FAD assembly factor SdhE Antitoxin
LQ191_RS04165 (AI2946V1_0816) 865044..865454 + 411 WP_004105559.1 protein YgfX Toxin
LQ191_RS04170 (AI2946V1_0817) 865463..865984 - 522 WP_004105557.1 flavodoxin FldB -
LQ191_RS04175 (AI2946V1_0818) 866106..867002 + 897 WP_004105555.1 site-specific tyrosine recombinase XerD -
LQ191_RS04180 (AI2946V1_0819) 867025..867738 + 714 WP_004105554.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
LQ191_RS04185 (AI2946V1_0820) 867744..869477 + 1734 WP_004105553.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16061.83 Da        Isoelectric Point: 10.9455

>T296049 WP_004105559.1 NZ_OW968280:865044-865454 [Klebsiella oxytoca]
VVLWQSDLRISWRAQWFSLLMHGVVAALVLVLPWPLSYTPLWLILLSLVVFDCVRSQRRIHARQGEIKLLIDSRLRWQKA
EWDIVGTPWVINSGMLLRLRNTENQRTQHLWVAADSMDAGEWRDLRRLVLQKPTQD

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10555.02 Da        Isoelectric Point: 5.1498

>AT296049 WP_004105561.1 NZ_OW968280:864797-865063 [Klebsiella oxytoca]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDTLSDDDKRLFIRLLENDDPDLFNWLMNHGEPADAELQRMVKLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A181X6I0

Antitoxin

Source ID Structure
AlphaFold DB A0A285B945

References