29601

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 14466..15001 Replicon plasmid p75
Accession NC_021594
Organism Serratia plymuthica 4Rx13

Toxin (Protein)


Gene name relE Uniprot ID A0A318NU54
Locus tag SOD_RS24410 Protein ID WP_041417419.1
Coordinates 14714..15001 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A318PAP2
Locus tag SOD_RS24405 Protein ID WP_004953896.1
Coordinates 14466..14717 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SOD_RS24375 11224..11688 + 465 WP_004953890.1 conjugation system SOS inhibitor PsiB -
SOD_RS24380 11685..12416 + 732 WP_004953894.1 plasmid SOS inhibition protein A -
SOD_RS24385 12489..12848 + 360 WP_041417418.1 hypothetical protein -
SOD_RS24395 13133..13366 - 234 WP_037430037.1 DNA polymerase III subunit theta -
SOD_RS24400 13924..14370 + 447 WP_020453968.1 hypothetical protein -
SOD_RS24405 14466..14717 + 252 WP_004953896.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
SOD_RS24410 14714..15001 + 288 WP_041417419.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
SOD_RS24415 15043..15276 + 234 WP_037430034.1 hypothetical protein -
SOD_RS24420 15966..16385 + 420 WP_020453969.1 hypothetical protein -
SOD_RS24425 16422..16772 + 351 WP_020453970.1 hypothetical protein -
SOD_RS24430 16859..17119 + 261 WP_041417420.1 hypothetical protein -
SOD_RS24435 17313..17951 + 639 WP_041417439.1 N-6 DNA methylase -
SOD_RS24440 17987..18214 + 228 WP_037430031.1 hypothetical protein -
SOD_RS24445 18804..19247 + 444 WP_006322790.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..75721 75721


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10885.95 Da        Isoelectric Point: 10.2779

>T29601 WP_041417419.1 NC_021594:14714-15001 [Serratia plymuthica 4Rx13]
MTYTVKFRESALKEWGKLDKVLQQQFAKKLKKCCENPHVPSAKLRGMPGCYKIKLRAAGYRLVYEVIDDILVIAVVAVGK
RERGDVYQLASERLK

Download         Length: 288 bp

>T29601 NC_021594:14714-15001 [Serratia plymuthica 4Rx13]
ATGACGTATACGGTCAAATTTCGTGAGTCGGCTCTGAAAGAGTGGGGAAAACTGGATAAGGTTCTTCAGCAGCAGTTTGC
TAAAAAGCTGAAAAAGTGTTGCGAGAACCCTCACGTCCCATCGGCGAAACTGCGTGGGATGCCGGGATGTTACAAGATCA
AGCTGCGTGCAGCGGGATATCGATTGGTCTATGAAGTGATCGACGACATCCTTGTAATCGCGGTTGTGGCCGTTGGCAAA
CGTGAACGGGGCGACGTCTATCAACTGGCCAGTGAACGCTTGAAATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9184.39 Da        Isoelectric Point: 3.9015

>AT29601 WP_004953896.1 NC_021594:14466-14717 [Serratia plymuthica 4Rx13]
MPNIILSDTSASISELKKNPMETVGAGDGFPVAILNRNQPAFYCVPAALYEQMLDALDDQELVRLVNERRSEALVDIDLD
QFS

Download         Length: 252 bp

>AT29601 NC_021594:14466-14717 [Serratia plymuthica 4Rx13]
ATGCCAAATATCATTTTGAGTGACACAAGTGCGAGCATCAGCGAGCTGAAGAAAAACCCTATGGAAACCGTTGGTGCCGG
TGACGGTTTTCCGGTGGCCATCCTGAACCGCAATCAGCCTGCATTCTATTGCGTGCCTGCGGCGCTCTATGAGCAAATGC
TCGATGCCCTTGATGATCAGGAGCTGGTGAGATTGGTCAATGAGCGCCGTAGCGAAGCGCTGGTTGATATCGATCTGGAT
CAGTTCTCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A318NU54

Antitoxin

Source ID Structure
AlphaFold DB A0A318PAP2

References