Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2244709..2244980 Replicon chromosome
Accession NZ_OW967966
Organism Escherichia coli isolate 648

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2244839..2244942 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2244709..2244980 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ127_RS10920 2241264..2241926 - 663 WP_000944256.1 exodeoxyribonuclease X -
LQ127_RS10925 2241950..2242606 - 657 WP_000011651.1 carbon-nitrogen hydrolase family protein YobB -
LQ127_RS10930 2242708..2242938 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LQ127_RS10935 2243077..2243451 + 375 WP_022645803.1 CopC domain-containing protein YobA -
LQ127_RS10940 2243455..2244327 + 873 WP_022645802.1 copper homeostasis membrane protein CopD -
LQ127_RS10945 2244340..2244681 + 342 WP_000976472.1 YebY family protein -
- 2244709..2244980 - 272 - - Antitoxin
- 2244839..2244942 + 104 - - Toxin
LQ127_RS10950 2245077..2245733 + 657 WP_022645801.1 protein-serine/threonine phosphatase -
LQ127_RS10955 2245734..2245925 - 192 WP_001296140.1 YebW family protein -
LQ127_RS10960 2246030..2246266 - 237 WP_001295499.1 YebV family protein -
LQ127_RS10965 2246384..2247823 - 1440 WP_024181822.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T295884 NZ_OW967966:2244839-2244942 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT295884 NZ_OW967966:c2244980-2244709 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References