Detailed information of TA system TA029588

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 1667243..1667768
• Replicon: chromosome
• Accession: NC_021591
• Organism: Serratia plymuthica 4Rx13

Toxin (Protein)

• Gene name: relE
• Uniprot ID: A0A318NZS7
• Locus tag: SOD_RS07715
• Protein ID: WP_041416849.1
• Coordinates: 1667243..1667527 (-)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: SOD_RS07720
• Protein ID: WP_041416850.1
• Coordinates: 1667517..1667768 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SOD_RS07690	1662501..1663634	+	1134	WP_037432607.1	putrescine ABC transporter ATP-binding subunit PotG	-
SOD_RS07695	1663665..1664624	+	960	WP_110605892.1	putrescine ABC transporter permease PotH	-
SOD_RS07700	1664621..1665466	+	846	WP_004942522.1	putrescine ABC transporter permease PotI	-
SOD_RS07705	1665569..1666048	+	480	WP_004942523.1	YbjO family protein	-
SOD_RS07710	1666119..1667246	+	1128	WP_004942524.1	23S rRNA (uracil(747)-C(5))-methyltransferase RlmC	-
SOD_RS07715	1667243..1667527	-	285	WP_041416849.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
SOD_RS07720	1667517..1667768	-	252	WP_041416850.1	prevent-host-death protein	Antitoxin
SOD_RS07725	1667868..1668602	-	735	WP_004942526.1	arginine ABC transporter substrate-binding protein	-
SOD_RS07730	1668809..1669477	-	669	WP_004942528.1	arginine ABC transporter permease ArtM	-
SOD_RS07735	1669477..1670193	-	717	WP_004942529.1	arginine ABC transporter permease ArtQ	-
SOD_RS07740	1670203..1670934	-	732	WP_004942530.1	arginine ABC transporter substrate-binding protein	-
SOD_RS07745	1670968..1671696	-	729	WP_004942535.1	arginine ABC transporter ATP-binding protein ArtP	-
SOD_RS07750	1671952..1672500	-	549	WP_004942538.1	lipoprotein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-84)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10823.79 Da
• Isoelectric Point: 9.8623

>T29588 WP_041416849.1 NC_021591:c1667527-1667243 [Serratia plymuthica 4Rx13]
MTYSLEFEEHALKEFKKLAPVLRDQFKKKLATVLENPCIPANRLSGLPDCYKIKLKASGYHLVYRVIDEEIVVLVLSIGK
RERSEAYTAAKKRL

Nucleotide

• Length: 285 bp

>T29588 NC_021591:c1667527-1667243 [Serratia plymuthica 4Rx13]
ATGACTTATAGCCTTGAATTCGAAGAACATGCACTAAAGGAATTTAAGAAACTGGCCCCGGTACTTCGGGATCAATTCAA
GAAAAAACTGGCAACAGTATTAGAAAATCCCTGTATTCCCGCCAATAGACTCTCTGGCCTACCGGATTGCTATAAAATAA
AACTTAAGGCTTCCGGTTACCATCTGGTCTATCGTGTCATCGACGAGGAGATTGTGGTGCTGGTGCTTTCGATAGGTAAG
CGTGAGCGTTCAGAGGCCTATACGGCTGCCAAAAAACGCCTTTAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9083.38 Da
• Isoelectric Point: 6.2821

>AT29588 WP_041416850.1 NC_021591:c1667768-1667517 [Serratia plymuthica 4Rx13]
MIVQPILANSAVSISDFKKSPNTALKEANGQPVAVLTNGKISGYYVSPETWEAISEYLEDIELAKTARSRMSGKRIKVNL
DDL

Nucleotide

• Length: 252 bp

>AT29588 NC_021591:c1667768-1667517 [Serratia plymuthica 4Rx13]
ATGATCGTTCAACCTATCCTCGCGAATTCAGCCGTCAGCATCAGTGATTTTAAAAAATCGCCTAACACTGCGCTCAAAGA
AGCCAACGGGCAACCTGTGGCAGTACTTACCAATGGAAAAATCTCCGGCTATTACGTCTCTCCGGAAACGTGGGAAGCAA
TCTCTGAATACCTGGAAGATATCGAACTCGCAAAAACAGCCCGCTCACGGATGAGCGGCAAACGTATTAAGGTCAATCTG
GATGACTTATAG

Structures

Toxin

• AlphaFold DB: A0A318NZS7