Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2197082..2197224 Replicon chromosome
Accession NZ_OW967518
Organism Klebsiella oxytoca isolate

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2197117..2197220 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2197082..2197224 (-)

Genomic Context


LQ214_RS10485LQ214_RS10500LQ214_RS10505LQ214_RS10510--LQ214_RS10490LQ214_RS10495--LQ214_RS10515LQ214_RS10520LQ214_RS10525LQ214_RS10530LQ214_RS10535LQ214_RS10540LQ214_RS10545LQ214_RS10550LQ214_RS10555
Location: 2192186..2194246 (2061 bp)
Type: Others
Protein ID: WP_016808307.1
Location: 2195357..2195731 (375 bp)
Type: Others
Protein ID: WP_024274401.1
Location: 2195736..2196605 (870 bp)
Type: Others
Protein ID: WP_004103346.1
Location: 2196622..2196960 (339 bp)
Type: Others
Protein ID: WP_004103344.1
Location: 2197117..2197220 (104 bp)
Type: Toxin
Protein ID: -
Location: 2194253..2194912 (660 bp)
Type: Others
Protein ID: WP_004103360.1
Location: 2194991..2195221 (231 bp)
Type: Others
Protein ID: WP_004103351.1
Location: 2197082..2197224 (143 bp)
Type: Antitoxin
Protein ID: -
Location: 2197298..2198383 (1086 bp)
Type: Others
Protein ID: WP_064351719.1
Location: 2198352..2198624 (273 bp)
Type: Others
Protein ID: WP_049101843.1
Location: 2198790..2199269 (480 bp)
Type: Others
Protein ID: WP_049101844.1
Location: 2199462..2199660 (199 bp)
Type: Others
Protein ID: Protein_2060
Location: 2199657..2200304 (648 bp)
Type: Others
Protein ID: WP_064351718.1
Location: 2200301..2200501 (201 bp)
Type: Others
Protein ID: WP_064351717.1
Location: 2200498..2200716 (219 bp)
Type: Others
Protein ID: WP_047721000.1
Location: 2200713..2201369 (657 bp)
Type: Others
Protein ID: WP_064351716.1
Location: 2201366..2201794 (429 bp)
Type: Others
Protein ID: WP_064351715.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LQ214_RS10485 (AI2744V1_2031)2192186..2194246+2061WP_016808307.1oligopeptidase B-
LQ214_RS10490 (AI2744V1_2032)2194253..2194912-660WP_004103360.1exodeoxyribonuclease X-
LQ214_RS10495 (AI2744V1_2033)2194991..2195221-231WP_004103351.1DNA polymerase III subunit theta-
LQ214_RS10500 (AI2744V1_2034)2195357..2195731+375WP_024274401.1CopC domain-containing protein YobA-
LQ214_RS10505 (AI2744V1_2035)2195736..2196605+870WP_004103346.1copper homeostasis membrane protein CopD-
LQ214_RS10510 (AI2744V1_2036)2196622..2196960+339WP_004103344.1YebY family protein-
-2197082..2197224-143--Antitoxin
-2197117..2197220+104--Toxin
LQ214_RS10515 (AI2744V1_2037)2197298..2198383-1086WP_064351719.1tyrosine-type recombinase/integrase-
LQ214_RS10520 (AI2744V1_2038)2198352..2198624-273WP_049101843.1excisionase-
LQ214_RS10525 (AI2744V1_2039)2198790..2199269-480WP_049101844.1hypothetical protein-
LQ214_RS105302199462..2199660-199Protein_2060DUF1382 family protein-
LQ214_RS10535 (AI2744V1_2040)2199657..2200304-648WP_064351718.1hypothetical protein-
LQ214_RS10540 (AI2744V1_2041)2200301..2200501-201WP_064351717.1hypothetical protein-
LQ214_RS10545 (AI2744V1_2042)2200498..2200716-219WP_047721000.1hypothetical protein-
LQ214_RS10550 (AI2744V1_2043)2200713..2201369-657WP_064351716.1MT-A70 family methyltransferase-
LQ214_RS10555 (AI2744V1_2044)2201366..2201794-429WP_064351715.1hypothetical protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideProphage--2192132..225572463592


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T295815 NZ_OW967518:2197117-2197220 [Klebsiella oxytoca]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTTTTTTT

Antitoxin


Download         Length: 143 bp

>AT295815 NZ_OW967518:c2197224-2197082 [Klebsiella oxytoca]
AGATAAAAAAAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTG
GCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References