Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2787533..2787732 Replicon chromosome
Accession NZ_OW967388
Organism Enterobacter cloacae isolate 114

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2787536..2787639 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2787533..2787732 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ218_RS13435 (AI2624V1_2617) 2783797..2785239 + 1443 WP_072199618.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
LQ218_RS13440 (AI2624V1_2618) 2785346..2785585 + 240 WP_003859885.1 YebV family protein -
LQ218_RS13445 (AI2624V1_2619) 2785620..2786264 - 645 WP_003859884.1 protein-serine/threonine phosphatase -
LQ218_RS13450 (AI2624V1_2620) 2786432..2787412 + 981 WP_003859879.1 VirK/YbjX family protein -
LQ218_RS13455 2787458..2787655 + 198 WP_032609507.1 hypothetical protein -
- 2787533..2787732 + 200 - - Antitoxin
- 2787536..2787639 - 104 - - Toxin
LQ218_RS13460 (AI2624V1_2621) 2787781..2788119 - 339 WP_003859787.1 YebY family protein -
LQ218_RS13465 (AI2624V1_2622) 2788136..2789005 - 870 WP_022651438.1 copper homeostasis membrane protein CopD -
LQ218_RS13470 (AI2624V1_2623) 2789007..2789378 - 372 WP_022651439.1 CopC domain-containing protein YobA -
LQ218_RS13475 (AI2624V1_2624) 2789516..2789746 + 231 WP_003859784.1 DNA polymerase III subunit theta -
LQ218_RS13480 (AI2624V1_2625) 2789858..2790508 + 651 WP_003859783.1 carbon-nitrogen hydrolase family protein -
LQ218_RS13485 (AI2624V1_2626) 2790533..2791195 + 663 WP_015570288.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T295806 NZ_OW967388:c2787639-2787536 [Enterobacter cloacae]
GGCAAGGCGATTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 200 bp

>AT295806 NZ_OW967388:2787533-2787732 [Enterobacter cloacae]
GATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGG
CATTAATGCAGGCTCAATCGCCTTGCCCTTTAAGAATAGATGACGACGTCAGGTTTTCCAGTCCACAGTAAAAGTGGTCT
GAAAAAAAGCGTCAGAACATCACTAAATGTGAAAAACCGC

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References