295797

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX(toxin)
Location 4764676..4765495 Replicon chromosome
Accession NZ_OW967374
Organism Klebsiella oxytoca isolate 145

Toxin (Protein)


Gene name yjhX Uniprot ID J5WT09
Locus tag LQ212_RS22670 Protein ID WP_004110819.1
Coordinates 4765238..4765495 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID -
Locus tag LQ212_RS22665 Protein ID WP_004099227.1
Coordinates 4764676..4765227 (-) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ212_RS22645 (AI2623V1_4439) 4760526..4761803 + 1278 WP_064344806.1 hypothetical protein -
LQ212_RS22650 (AI2623V1_4440) 4761821..4762984 + 1164 WP_064344805.1 MFS transporter -
LQ212_RS22655 4763030..4763794 - 765 WP_224238718.1 class I SAM-dependent methyltransferase -
LQ212_RS22660 4764188..4764562 - 375 Protein_4466 class I SAM-dependent methyltransferase -
LQ212_RS22665 (AI2623V1_4442) 4764676..4765227 - 552 WP_004099227.1 N-acetyltransferase Antitoxin
LQ212_RS22670 (AI2623V1_4443) 4765238..4765495 - 258 WP_004110819.1 YjhX family toxin Toxin
LQ212_RS22675 (AI2623V1_4444) 4766077..4767261 + 1185 WP_004099225.1 mannonate dehydratase -
LQ212_RS22680 (AI2623V1_4445) 4767336..4768811 + 1476 WP_004110817.1 fructuronate reductase -
LQ212_RS22685 (AI2623V1_4446) 4768947..4769723 + 777 WP_017146569.1 Uxu operon transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin

GNAT domain

(17-121)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9552.07 Da        Isoelectric Point: 11.1381

>T295797 WP_004110819.1 NZ_OW967374:c4765495-4765238 [Klebsiella oxytoca]
MNLSRQEQRTLHVLAKGGRIAHIRDASGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 20246.21 Da        Isoelectric Point: 6.7178

>AT295797 WP_004099227.1 NZ_OW967374:c4765227-4764676 [Klebsiella oxytoca]
MTNHNFTFHITSERDADDIREVETRAFGFSKEADLVADLLNDESAHPRLSLLAKHNGKAVGHILFTLATFKGESDSPMMH
ILAPLAVVPEYQGMGVGGLLIQSGIEHLKAMGSLAVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMLQRLSS
RPLGITGQIQCARALMKPEHWRE

Download         Length: 552 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H3H6Y2

Antitoxin

Source ID Structure

References