295791

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 1308170..1308953 Replicon chromosome
Accession NZ_OW967374
Organism Klebsiella oxytoca isolate 145

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag LQ212_RS06315 Protein ID WP_010434197.1
Coordinates 1308170..1308544 (-) Length 125 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag LQ212_RS06320 Protein ID WP_024274583.1
Coordinates 1308594..1308953 (-) Length 120 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ212_RS06290 (AI2623V1_1232) 1303842..1304075 - 234 WP_004132711.1 hypothetical protein -
LQ212_RS06295 (AI2623V1_1233) 1304485..1304757 + 273 WP_016247220.1 hypothetical protein -
LQ212_RS06300 (AI2623V1_1234) 1304960..1305868 + 909 WP_024274585.1 kdo(2)-lipid IV(A) palmitoleoyltransferase -
LQ212_RS06305 (AI2623V1_1235) 1306642..1307631 + 990 WP_010434201.1 glycosyltransferase -
LQ212_RS06310 (AI2623V1_1236) 1307635..1308090 + 456 WP_226859238.1 hypothetical protein -
LQ212_RS06315 (AI2623V1_1238) 1308170..1308544 - 375 WP_010434197.1 TA system toxin CbtA family protein Toxin
LQ212_RS06320 (AI2623V1_1239) 1308594..1308953 - 360 WP_024274583.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
LQ212_RS06325 (AI2623V1_1240) 1308976..1309197 - 222 WP_024274582.1 DUF987 domain-containing protein -
LQ212_RS06330 (AI2623V1_1241) 1309211..1309693 - 483 WP_024274581.1 DNA repair protein RadC -
LQ212_RS06335 (AI2623V1_1242) 1309690..1309923 - 234 WP_010434188.1 hypothetical protein -
LQ212_RS06340 (AI2623V1_1243) 1309934..1310413 - 480 WP_010434186.1 antirestriction protein -
LQ212_RS06345 (AI2623V1_1244) 1310492..1311313 - 822 WP_010434183.1 DUF932 domain-containing protein -
LQ212_RS06350 (AI2623V1_1245) 1311424..1311636 - 213 WP_010434180.1 hypothetical protein -
LQ212_RS06355 (AI2623V1_1246) 1311717..1312076 - 360 WP_010434179.1 hypothetical protein -
LQ212_RS06360 (AI2623V1_1247) 1312131..1312595 - 465 WP_024274580.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - algU 1306642..1429944 123302


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(8-112)

Antitoxin

Antitoxin CbeA

(15-114)


Sequences

Toxin        


Download         Length: 125 a.a.        Molecular weight: 13977.96 Da        Isoelectric Point: 9.6955

>T295791 WP_010434197.1 NZ_OW967374:c1308544-1308170 [Klebsiella oxytoca]
MQIHSLFLQRAASSRLSSVEIWQKLLEYLLEQHYGLTLNDTPFGNDSVIQKHIDAGISLYDAVNFIVEKYDLVRTDRHGF
SVKEQSPFIGSLDILRARKATGLMTRKGYKTVTDITGGRFSGGK

Download         Length: 375 bp

Antitoxin


Download         Length: 120 a.a.        Molecular weight: 13469.67 Da        Isoelectric Point: 7.7511

>AT295791 WP_024274583.1 NZ_OW967374:c1308953-1308594 [Klebsiella oxytoca]
MKKATRVINHNITEPWWGLRRNITPCFGARLVQEGNHLHYLADRASIAGTFNDADLRHLDQVFPVLMKQMELMLASSELT
PRIQRCITLHVKGLICEADTLGSCGYLYIVIYPASVTTE

Download         Length: 360 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References