Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2092607..2092878 Replicon chromosome
Accession NZ_OW967178
Organism Escherichia coli isolate 362

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2092737..2092840 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2092607..2092878 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ124_RS09920 2089162..2089824 - 663 WP_000944256.1 exodeoxyribonuclease X -
LQ124_RS09925 2089848..2090504 - 657 WP_000011660.1 carbon-nitrogen hydrolase family protein YobB -
LQ124_RS09930 2090606..2090836 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LQ124_RS09935 2090975..2091349 + 375 WP_000168743.1 CopC domain-containing protein YobA -
LQ124_RS09940 2091353..2092225 + 873 WP_000879330.1 copper homeostasis membrane protein CopD -
LQ124_RS09945 2092238..2092579 + 342 WP_000976474.1 YebY family protein -
- 2092607..2092878 - 272 - - Antitoxin
- 2092737..2092840 + 104 - - Toxin
LQ124_RS09950 2092975..2093631 + 657 WP_001590231.1 protein-serine/threonine phosphatase -
LQ124_RS09955 2093632..2093823 - 192 WP_001296140.1 YebW family protein -
LQ124_RS09960 2093928..2094164 - 237 WP_001295499.1 YebV family protein -
LQ124_RS09965 2094282..2095721 - 1440 WP_024196367.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2085297..2095727 10430


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T295759 NZ_OW967178:2092737-2092840 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT295759 NZ_OW967178:c2092878-2092607 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References