Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yjhX-yjhQ/YjhX(toxin) |
Location | 4606914..4607733 | Replicon | chromosome |
Accession | NZ_OW849470 | ||
Organism | Klebsiella oxytoca isolate 325 |
Toxin (Protein)
Gene name | yjhX | Uniprot ID | - |
Locus tag | LQ213_RS21680 | Protein ID | WP_064372979.1 |
Coordinates | 4607476..4607733 (-) | Length | 86 a.a. |
Antitoxin (Protein)
Gene name | yjhQ | Uniprot ID | - |
Locus tag | LQ213_RS21675 | Protein ID | WP_230186121.1 |
Coordinates | 4606914..4607465 (-) | Length | 184 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LQ213_RS21655 (AI2699V1_4223) | 4602243..4603640 | + | 1398 | WP_230186119.1 | MFS transporter | - |
LQ213_RS21660 (AI2699V1_4224) | 4603764..4605104 | + | 1341 | WP_230186120.1 | carbohydrate porin | - |
LQ213_RS21665 | 4605268..4606032 | - | 765 | WP_227629826.1 | class I SAM-dependent methyltransferase | - |
LQ213_RS21670 | 4606426..4606800 | - | 375 | Protein_4265 | class I SAM-dependent methyltransferase | - |
LQ213_RS21675 (AI2699V1_4226) | 4606914..4607465 | - | 552 | WP_230186121.1 | N-acetyltransferase | Antitoxin |
LQ213_RS21680 (AI2699V1_4227) | 4607476..4607733 | - | 258 | WP_064372979.1 | YjhX family toxin | Toxin |
LQ213_RS21685 (AI2699V1_4228) | 4608315..4609499 | + | 1185 | WP_230186122.1 | mannonate dehydratase | - |
LQ213_RS21690 (AI2699V1_4229) | 4609574..4611049 | + | 1476 | WP_004110817.1 | fructuronate reductase | - |
LQ213_RS21695 (AI2699V1_4230) | 4611185..4611961 | + | 777 | WP_017146569.1 | Uxu operon transcriptional regulator | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 86 a.a. Molecular weight: 9564.12 Da Isoelectric Point: 11.1381
>T295710 WP_064372979.1 NZ_OW849470:c4607733-4607476 [Klebsiella oxytoca]
MNLSRQEQRTLHVLAKGGRIAHIRDASGRVISVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR
MNLSRQEQRTLHVLAKGGRIAHIRDASGRVISVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR
Download Length: 258 bp
Antitoxin
Download Length: 184 a.a. Molecular weight: 20195.04 Da Isoelectric Point: 6.7181
>AT295710 WP_230186121.1 NZ_OW849470:c4607465-4606914 [Klebsiella oxytoca]
MTNHNFTFHITSERDADDIREVETRAFGFSKEADLVADLLNDESAHPSLSLLAKHNGKAVGHILFTLATFKGESDSPMMH
ILAPLAVVPEYQGVGVGGLLIQRGIEHLKAAGSEAVFVLGHAAYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMLQRLSS
RPLGRIGQIQCARALMKPEHWRE
MTNHNFTFHITSERDADDIREVETRAFGFSKEADLVADLLNDESAHPSLSLLAKHNGKAVGHILFTLATFKGESDSPMMH
ILAPLAVVPEYQGVGVGGLLIQRGIEHLKAAGSEAVFVLGHAAYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMLQRLSS
RPLGRIGQIQCARALMKPEHWRE
Download Length: 552 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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