Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 781265..782100 Replicon chromosome
Accession NZ_OW849377
Organism Escherichia coli isolate 162

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag LQ158_RS03805 Protein ID WP_063090830.1
Coordinates 781265..781642 (-) Length 126 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag LQ158_RS03810 Protein ID WP_024174331.1
Coordinates 781732..782100 (-) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ158_RS03775 (776673) 776673..777650 + 978 WP_000633235.1 type II secretion system minor pseudopilin GspK -
LQ158_RS03780 (777647) 777647..778825 + 1179 WP_000094957.1 type II secretion system protein GspL -
LQ158_RS03785 (778827) 778827..779363 + 537 WP_000942795.1 GspM family type II secretion system protein YghD -
LQ158_RS03790 (779644) 779644..780486 - 843 WP_042096658.1 DUF4942 domain-containing protein -
LQ158_RS03795 (780571) 780571..780768 - 198 WP_000838536.1 DUF957 domain-containing protein -
LQ158_RS03800 (780780) 780780..781268 - 489 WP_042096656.1 DUF5983 family protein -
LQ158_RS03805 (781265) 781265..781642 - 378 WP_063090830.1 TA system toxin CbtA family protein Toxin
LQ158_RS03810 (781732) 781732..782100 - 369 WP_024174331.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
LQ158_RS03815 (782174) 782174..782395 - 222 WP_000692346.1 DUF987 domain-containing protein -
LQ158_RS03820 (782464) 782464..782940 - 477 WP_001186725.1 RadC family protein -
LQ158_RS03825 (782956) 782956..783441 - 486 WP_042096390.1 antirestriction protein -
LQ158_RS03830 (783533) 783533..784351 - 819 WP_001234749.1 DUF932 domain-containing protein -
LQ158_RS03835 (784442) 784442..784675 - 234 WP_001117568.1 DUF905 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-112)

Antitoxin

Antitoxin CbeA

(19-117)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 14210.15 Da        Isoelectric Point: 6.8518

>T295677 WP_063090830.1 NZ_OW849377:c781642-781265 [Escherichia coli]
MNTLPDTHVREASRCPSPVTIWQTLLTRLLDQHYGLTLNDTPFADERVIEQHIEAGISLCDAVNFLVEKYALVRTDQLGF
SACTRSQLINSIDILRARRATGLMTRDNYRMVNNITQGKHPEAQQ

Download         Length: 378 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 13603.42 Da        Isoelectric Point: 6.7386

>AT295677 WP_024174331.1 NZ_OW849377:c782100-781732 [Escherichia coli]
VSDTLPGTTHPDDNHDRLWWGLPCTVTPCFGARLVQKGNRLHYLADRAGIRGRFSDADAYHLDQAFPLLMKQLELMLTSG
ELNPRHQHTVTLYAKGLTCEADTLGSCGYVYLAVYPTPETKT

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References