Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2916486..2916640 Replicon chromosome
Accession NZ_OW849195
Organism Enterobacter cloacae isolate 125

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2916502..2916605 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2916486..2916640 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ145_RS14270 (AI2762V1_2794) 2912764..2914206 + 1443 WP_032629037.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
LQ145_RS14275 (AI2762V1_2795) 2914312..2914551 + 240 WP_008500472.1 YebV family protein -
LQ145_RS14280 (AI2762V1_2796) 2914585..2915229 - 645 WP_023330645.1 protein-serine/threonine phosphatase -
LQ145_RS14285 (AI2762V1_2797) 2915397..2916338 + 942 WP_014884298.1 VirK/YbjX family protein -
- 2916486..2916640 + 155 - - Antitoxin
- 2916502..2916605 - 104 - - Toxin
LQ145_RS14290 (AI2762V1_2798) 2916744..2917082 - 339 WP_014884299.1 YebY family protein -
LQ145_RS14295 (AI2762V1_2799) 2917099..2917968 - 870 WP_023330712.1 copper homeostasis membrane protein CopD -
LQ145_RS14300 (AI2762V1_2800) 2917970..2918341 - 372 WP_023330713.1 CopC domain-containing protein YobA -
LQ145_RS14305 (AI2762V1_2801) 2918479..2918709 + 231 WP_013096102.1 DNA polymerase III subunit theta -
LQ145_RS14310 (AI2762V1_2802) 2918820..2919470 + 651 WP_014884302.1 carbon-nitrogen hydrolase family protein -
LQ145_RS14315 (AI2762V1_2803) 2919495..2920157 + 663 WP_014884303.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T295668 NZ_OW849195:c2916605-2916502 [Enterobacter cloacae]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 155 bp

>AT295668 NZ_OW849195:2916486-2916640 [Enterobacter cloacae]
TGTCTTTCATACAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTG
CGCTAAAAGTTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTTTAAGAATAGATGACGACGCCAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References