Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 453769..454364 Replicon chromosome
Accession NZ_OW849195
Organism Enterobacter cloacae isolate 125

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag LQ145_RS02145 Protein ID WP_023331877.1
Coordinates 454014..454364 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag LQ145_RS02140 Protein ID WP_023331876.1
Coordinates 453769..454020 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ145_RS02130 (AI2762V1_0414) 449436..453212 + 3777 WP_023331875.1 autotransporter assembly complex protein TamB -
LQ145_RS02135 (AI2762V1_0415) 453215..453559 + 345 WP_014882267.1 gamma-glutamylcyclotransferase -
LQ145_RS02140 (AI2762V1_0416) 453769..454020 + 252 WP_023331876.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
LQ145_RS02145 (AI2762V1_0417) 454014..454364 + 351 WP_023331877.1 type II toxin-antitoxin system ChpB family toxin Toxin
LQ145_RS02150 (AI2762V1_0418) 454442..454972 - 531 WP_008501423.1 inorganic diphosphatase -
LQ145_RS02155 (AI2762V1_0419) 455282..456238 + 957 WP_014882271.1 galactofuranose ABC transporter substrate-binding protein YtfQ -
LQ145_RS02160 (AI2762V1_0420) 456370..457872 + 1503 WP_023331878.1 sugar ABC transporter ATP-binding protein -
LQ145_RS02165 (AI2762V1_0421) 457883..458908 + 1026 WP_014882273.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(7-115)

Antitoxin

Antitoxin PemI-like

(1-83)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12339.36 Da        Isoelectric Point: 6.9493

>T295664 WP_023331877.1 NZ_OW849195:454014-454364 [Enterobacter cloacae]
MVKRPCFERGDIVLVGFDPANGHEQKGAGRPALVLSVSAFNQLGMTLVAPVTQGGNFARYAGFSVPLSCEEGNILGVILV
NQIRMMDLGARLAKRIGVASDETVEDALLRLQAILS

Download         Length: 351 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9074.44 Da        Isoelectric Point: 4.2517

>AT295664 WP_023331876.1 NZ_OW849195:453769-454020 [Enterobacter cloacae]
MRITIKKWGNSAGMVIPGVVMKELGLKPGQSMEAQVTNNQLVLTPVSKQYSLEELLAQCDMSAPEINEQDVWGTSGPIGD
EVW

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References