Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2032414..2032555 Replicon chromosome
Accession NZ_OW849099
Organism Citrobacter freundii isolate 402

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2032449..2032552 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2032414..2032555 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ100_RS09725 2028861..2029523 - 663 WP_003833802.1 exodeoxyribonuclease X -
LQ100_RS09730 2029547..2030203 - 657 WP_060855110.1 carbon-nitrogen hydrolase family protein -
LQ100_RS09735 2030310..2030540 - 231 WP_003034925.1 DNA polymerase III subunit theta -
LQ100_RS09740 2030684..2031058 + 375 WP_003034928.1 CopC domain-containing protein YobA -
LQ100_RS09745 2031062..2031934 + 873 WP_060855111.1 copper homeostasis membrane protein CopD -
LQ100_RS09750 2031955..2032293 + 339 WP_060855112.1 YebY family protein -
- 2032414..2032555 - 142 - - Antitoxin
- 2032449..2032552 + 104 - - Toxin
LQ100_RS09755 2032685..2033764 - 1080 WP_016150458.1 phage integrase Arm DNA-binding domain-containing protein -
LQ100_RS09760 2033742..2034002 - 261 WP_230142764.1 excisionase -
LQ100_RS09765 2034066..2036537 - 2472 WP_060855113.1 exonuclease -
LQ100_RS09770 2036679..2037017 - 339 WP_230141588.1 Rrf2 family transcriptional regulator -
LQ100_RS09775 2037067..2037279 - 213 WP_153070801.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2026792..2080481 53689


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T295654 NZ_OW849099:2032449-2032552 [Citrobacter freundii]
GGCAGGGTAACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 142 bp

>AT295654 NZ_OW849099:c2032555-2032414 [Citrobacter freundii]
GATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGG
CATTAATGCAGGCTAAGTTACCCTGCCATTTAAGAATAGATGACAGCGCCAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References