Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | shpAB/BrnT-BrnA |
Location | 4135527..4136103 | Replicon | chromosome |
Accession | NZ_OW849064 | ||
Organism | Escherichia coli isolate 131 |
Toxin (Protein)
Gene name | shpA | Uniprot ID | A0A061KXE4 |
Locus tag | LQ135_RS20450 | Protein ID | WP_001295743.1 |
Coordinates | 4135527..4135814 (+) | Length | 96 a.a. |
Antitoxin (Protein)
Gene name | shpB | Uniprot ID | A0A066STF6 |
Locus tag | LQ135_RS20455 | Protein ID | WP_000063148.1 |
Coordinates | 4135801..4136103 (+) | Length | 101 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LQ135_RS20435 (4131187) | 4131187..4132491 | - | 1305 | WP_000535012.1 | restriction endonuclease subunit S | - |
LQ135_RS20440 (4132481) | 4132481..4134100 | - | 1620 | WP_001029745.1 | class I SAM-dependent DNA methyltransferase | - |
LQ135_RS20445 (4134164) | 4134164..4135330 | - | 1167 | WP_000800831.1 | restriction endonuclease | - |
LQ135_RS20450 (4135527) | 4135527..4135814 | + | 288 | WP_001295743.1 | BrnT family toxin | Toxin |
LQ135_RS20455 (4135801) | 4135801..4136103 | + | 303 | WP_000063148.1 | BrnA antitoxin family protein | Antitoxin |
LQ135_RS20460 (4136137) | 4136137..4137093 | - | 957 | WP_001295745.1 | GTPase | - |
LQ135_RS20465 (4137104) | 4137104..4137307 | - | 204 | WP_000467859.1 | YbdD/YjiX family protein | - |
LQ135_RS20470 (4137357) | 4137357..4139507 | - | 2151 | WP_001295524.1 | pyruvate/proton symporter BtsT | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A061KXE4 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A066STF6 |