Detailed information of TA system TA029559

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PP_4151-4152/excise(antitoxin)
• Location: 1866052..1867091
• Replicon: chromosome
• Accession: NC_021505
• Organism: Pseudomonas putida NBRC 14164

Toxin (Protein)

• Gene name: PP_4152
• Uniprot ID: -
• Locus tag: PP4_RS08180
• Protein ID: WP_016498726.1
• Coordinates: 1866052..1866627 (-)
• Length: 192 a.a.

Antitoxin (Protein)

• Gene name: PP_4151
• Uniprot ID: -
• Locus tag: PP4_RS08185
• Protein ID: WP_016498727.1
• Coordinates: 1866624..1867091 (-)
• Length: 156 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PP4_RS08170	1861660..1862895	+	1236	WP_041167657.1	FAD-dependent oxidoreductase	-
PP4_RS08175	1862899..1865829	-	2931	WP_016498725.1	aminotransferase	-
PP4_RS08180	1866052..1866627	-	576	WP_016498726.1	PIN domain-containing protein	Toxin
PP4_RS08185	1866624..1867091	-	468	WP_016498727.1	helix-turn-helix domain-containing protein	Antitoxin
PP4_RS08190	1867274..1867537	-	264	Protein_1609	DUF3077 domain-containing protein	-
PP4_RS08195	1867776..1869386	-	1611	WP_016498728.1	ABC transporter ATP-binding protein	-
PP4_RS08200	1869388..1870407	-	1020	WP_016498729.1	ABC transporter permease	-
PP4_RS08205	1870409..1871482	-	1074	WP_016498730.1	microcin C ABC transporter permease YejB	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (9-115)

Antitoxin

• Helix-turn-helix domain, group 17 (84-132)

Sequences

Toxin

Protein

• Length: 192 a.a.
• Molecular weight: 21599.76 Da
• Isoelectric Point: 5.0339

>T29559 WP_016498726.1 NC_021505:c1866627-1866052 [Pseudomonas putida NBRC 14164]
MKHSPFTAIYDANVLYPAPLRDFLMNLALTGIYRARWSAGIHDEWKRNLLLNRPDLTPEHVDRTSSLMDAAVPDALVTDY
DSPVEGLDLPDEDDRHVLAAAIKCNASVIVTFNLKDFPKSVLGVFDIEPLHPDDFIADLWDLDKAAVLEAAQRQRISLKN
PPHSVQQYLDRLLQQKLPETVKLLSGFKFLL

Nucleotide

• Length: 576 bp

>T29559 NC_021505:c1866627-1866052 [Pseudomonas putida NBRC 14164]
ATGAAGCACTCGCCCTTCACGGCCATATACGACGCGAACGTACTTTACCCTGCTCCCCTGCGTGATTTCCTGATGAACCT
GGCGCTGACGGGTATTTACCGGGCACGCTGGTCAGCGGGCATTCATGACGAGTGGAAGCGCAATCTGCTACTCAACCGAC
CTGACCTTACGCCTGAACATGTGGATCGCACGTCATCGCTGATGGATGCTGCGGTACCAGATGCACTCGTCACTGACTAC
GATTCACCGGTCGAAGGACTGGACTTGCCAGATGAGGATGATCGACATGTCCTCGCAGCAGCAATAAAGTGCAACGCCTC
GGTCATCGTCACCTTCAATTTGAAGGATTTTCCCAAGTCGGTTCTCGGGGTCTTCGATATTGAACCCTTGCATCCGGACG
ACTTCATCGCTGACCTGTGGGACCTGGACAAGGCAGCAGTCCTCGAAGCTGCCCAGCGCCAGCGAATATCGTTGAAGAAC
CCACCTCATAGCGTGCAGCAGTATCTCGACAGGCTGCTTCAGCAGAAGCTTCCCGAGACAGTGAAATTGCTTTCAGGATT
CAAGTTCCTCCTGTGA

Antitoxin

Protein

• Length: 156 a.a.
• Molecular weight: 17220.62 Da
• Isoelectric Point: 6.1059

>AT29559 WP_016498727.1 NC_021505:c1867091-1866624 [Pseudomonas putida NBRC 14164]
MTTANLSRNVLPDEKEIAVSVESSRTLAAFLSTKSDTQRIELLNEENQRQVVEVPTFALRLFGEILSELALGNSVKVVPI
HAELTTQEAADLLNVSRPHLVKLLDEAVIPHTKTGRHRRVRFSDLVAYKDQRDGVSRAAMDALAAQAQELKMGYE

Nucleotide

• Length: 468 bp

>AT29559 NC_021505:c1867091-1866624 [Pseudomonas putida NBRC 14164]
ATGACAACCGCCAACCTCTCTCGCAATGTTCTTCCTGATGAAAAAGAAATTGCCGTGTCTGTCGAGTCAAGCCGCACGCT
AGCGGCGTTCCTCTCGACAAAATCAGATACCCAACGGATCGAACTGCTCAACGAGGAAAATCAGCGCCAGGTTGTTGAAG
TGCCTACTTTCGCCCTACGCCTGTTCGGCGAGATTCTCAGCGAGCTGGCGTTGGGGAACTCGGTCAAAGTCGTCCCAATC
CACGCCGAACTGACGACCCAGGAAGCAGCAGACCTGCTTAACGTCTCCCGGCCGCACTTGGTAAAGCTGCTCGACGAAGC
GGTGATTCCGCACACCAAGACGGGCCGCCATCGGCGTGTCAGATTCTCCGACCTGGTTGCCTACAAGGACCAACGTGACG
GGGTGAGCCGCGCTGCAATGGATGCGCTGGCAGCCCAAGCTCAGGAATTGAAGATGGGGTACGAATGA