Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) shpAB/BrnT-BrnA
Location 4336765..4337341 Replicon chromosome
Accession NZ_OW848788
Organism Citrobacter freundii isolate 112

Toxin (Protein)


Gene name shpA Uniprot ID -
Locus tag LQ087_RS21235 Protein ID WP_003019170.1
Coordinates 4337054..4337341 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name shpB Uniprot ID -
Locus tag LQ087_RS21230 Protein ID WP_230122311.1
Coordinates 4336765..4337067 (-) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ087_RS21210 (4332487) 4332487..4333035 + 549 WP_003845610.1 hypothetical protein -
LQ087_RS21215 (4333278) 4333278..4335428 + 2151 WP_003845609.1 pyruvate/proton symporter BtsT -
LQ087_RS21220 (4335539) 4335539..4335733 + 195 WP_003830038.1 YbdD/YjiX family protein -
LQ087_RS21225 (4335746) 4335746..4336702 + 957 WP_230122310.1 GTPase -
LQ087_RS21230 (4336765) 4336765..4337067 - 303 WP_230122311.1 BrnA antitoxin family protein Antitoxin
LQ087_RS21235 (4337054) 4337054..4337341 - 288 WP_003019170.1 BrnT family toxin Toxin
LQ087_RS21240 (4337576) 4337576..4338742 + 1167 WP_230122312.1 restriction endonuclease -
LQ087_RS21245 (4338838) 4338838..4341267 + 2430 WP_230122313.1 DEAD/DEAH box helicase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(7-88)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(39-93)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11157.53 Da        Isoelectric Point: 7.0746

>T295559 WP_003019170.1 NZ_OW848788:c4337341-4337054 [Citrobacter freundii]
MPMEFEWDANKAQSNLRKHGVRFEDAVLVFDDPQHLSRQDRHENGEYRWQTIGLVHGIVVILVAHSVRFESGFEVIRIIS
ARKADSKERNRYEHG

Download         Length: 288 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11419.05 Da        Isoelectric Point: 9.5755

>AT295559 WP_230122311.1 NZ_OW848788:c4337067-4336765 [Citrobacter freundii]
MSMVKHKCGSVSALSAQHEAELKALANKPDDDIDYSDIPVTEDKQWSEATRGKFFRPLKTQASVRIDADVMEWLKRPGKG
YQTRLNAILREAMLREQNKK

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References