Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2193844..2193986 Replicon chromosome
Accession NZ_OW848788
Organism Citrobacter freundii isolate 112

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2193879..2193982 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2193844..2193986 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ087_RS10810 2190291..2190953 - 663 WP_003841659.1 exodeoxyribonuclease X -
LQ087_RS10815 2190977..2191633 - 657 WP_046671220.1 carbon-nitrogen hydrolase family protein -
LQ087_RS10820 2191740..2191970 - 231 WP_003034925.1 DNA polymerase III subunit theta -
LQ087_RS10825 2192114..2192488 + 375 WP_230121916.1 CopC domain-containing protein YobA -
LQ087_RS10830 2192492..2193364 + 873 WP_048232225.1 copper homeostasis membrane protein CopD -
LQ087_RS10835 2193385..2193723 + 339 WP_003034934.1 YebY family protein -
- 2193844..2193986 - 143 - - Antitoxin
- 2193879..2193982 + 104 - - Toxin
LQ087_RS10840 2194061..2195146 - 1086 WP_019076535.1 phage integrase Arm DNA-binding domain-containing protein -
LQ087_RS10845 2195115..2195387 - 273 WP_071684411.1 excisionase -
LQ087_RS10850 2195451..2195693 - 243 WP_137375969.1 DUF4060 family protein -
LQ087_RS10855 2195690..2195884 - 195 WP_016156723.1 hypothetical protein -
LQ087_RS10860 2195877..2196221 - 345 WP_230121917.1 hypothetical protein -
LQ087_RS10865 2196256..2197368 - 1113 WP_230122431.1 RecT family recombinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2188222..2239054 50832


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T295552 NZ_OW848788:2193879-2193982 [Citrobacter freundii]
GGCAGGGTAACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 143 bp

>AT295552 NZ_OW848788:c2193986-2193844 [Citrobacter freundii]
AGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTG
GCATTAATGCAGGCTAAGTTACCCTGCCATTTAAGAATAGATGACAGCGCCAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References