Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | shpAB/BrnT-BrnA |
Location | 3524964..3525540 | Replicon | chromosome |
Accession | NZ_OW848785 | ||
Organism | Escherichia coli isolate 131 |
Toxin (Protein)
Gene name | shpA | Uniprot ID | A0A061KXE4 |
Locus tag | LQ117_RS16975 | Protein ID | WP_001295743.1 |
Coordinates | 3524964..3525251 (+) | Length | 96 a.a. |
Antitoxin (Protein)
Gene name | shpB | Uniprot ID | A0A066STF6 |
Locus tag | LQ117_RS16980 | Protein ID | WP_000063148.1 |
Coordinates | 3525238..3525540 (+) | Length | 101 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LQ117_RS16960 (3520624) | 3520624..3521928 | - | 1305 | WP_000535012.1 | restriction endonuclease subunit S | - |
LQ117_RS16965 (3521918) | 3521918..3523537 | - | 1620 | WP_001029745.1 | class I SAM-dependent DNA methyltransferase | - |
LQ117_RS16970 (3523601) | 3523601..3524767 | - | 1167 | WP_000800831.1 | restriction endonuclease | - |
LQ117_RS16975 (3524964) | 3524964..3525251 | + | 288 | WP_001295743.1 | BrnT family toxin | Toxin |
LQ117_RS16980 (3525238) | 3525238..3525540 | + | 303 | WP_000063148.1 | BrnA antitoxin family protein | Antitoxin |
LQ117_RS16985 (3525574) | 3525574..3526530 | - | 957 | WP_001295745.1 | GTPase | - |
LQ117_RS16990 (3526541) | 3526541..3526744 | - | 204 | WP_000467859.1 | YbdD/YjiX family protein | - |
LQ117_RS16995 (3526794) | 3526794..3528944 | - | 2151 | WP_001295524.1 | pyruvate/proton symporter BtsT | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A061KXE4 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A066STF6 |