Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | V | Classification (family/domain) | ghoTS/ghoT-GhoS |
Location | 3197417..3197914 | Replicon | chromosome |
Accession | NZ_OW848785 | ||
Organism | Escherichia coli isolate 131 |
Toxin (Protein)
Gene name | ghoT | Uniprot ID | L4JJG6 |
Locus tag | LQ117_RS15300 | Protein ID | WP_001173343.1 |
Coordinates | 3197741..3197914 (+) | Length | 58 a.a. |
Antitoxin (Protein)
Gene name | ghoS | Uniprot ID | S1NQ59 |
Locus tag | LQ117_RS15295 | Protein ID | WP_001312331.1 |
Coordinates | 3197417..3197713 (+) | Length | 99 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LQ117_RS15285 (3192774) | 3192774..3196703 | + | 3930 | WP_001080129.1 | autotransporter outer membrane beta-barrel domain-containing protein | - |
LQ117_RS15290 (3196917) | 3196917..3197189 | + | 273 | WP_000405647.1 | GNAT family N-acetyltransferase | - |
LQ117_RS15295 (3197417) | 3197417..3197713 | + | 297 | WP_001312331.1 | type V toxin-antitoxin system endoribonuclease antitoxin GhoS | Antitoxin |
LQ117_RS15300 (3197741) | 3197741..3197914 | + | 174 | WP_001173343.1 | type V toxin-antitoxin system toxin GhoT | Toxin |
LQ117_RS15305 (3198033) | 3198033..3199550 | - | 1518 | WP_000003806.1 | lysine--tRNA ligase | - |
LQ117_RS15310 (3199787) | 3199787..3201244 | - | 1458 | WP_000856826.1 | dipeptide/tripeptide permease DtpC | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | - | 3181826..3243472 | 61646 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7U9QI41 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | S1NQ59 |