Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3765638..3765781 Replicon chromosome
Accession NZ_OW707734
Organism Salmonella enterica subsp. enterica serovar Typhi strain BRD948

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3765640..3765742 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3765638..3765781 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NBX04_RS18675 3762916..3764046 + 1131 WP_000529513.1 GGDEF domain-containing protein -
NBX04_RS18680 3764332..3764727 - 396 Protein_3645 DUF977 family protein -
NBX04_RS18685 3764740..3764850 - 111 Protein_3646 replication protein -
NBX04_RS18690 3764851..3765212 + 362 Protein_3647 recombinase RecT -
NBX04_RS18695 3765211..3765519 + 309 Protein_3648 tyrosine-type recombinase/integrase -
- 3765638..3765781 + 144 - - Antitoxin
- 3765640..3765742 - 103 - - Toxin
NBX04_RS18700 3765883..3766236 - 354 WP_000722366.1 YebY family protein -
NBX04_RS18705 3766253..3767128 - 876 WP_000979693.1 copper homeostasis membrane protein CopD -
NBX04_RS18710 3767129..3767503 - 375 WP_001681742.1 CopC domain-containing protein YobA -
NBX04_RS18715 3767641..3767871 + 231 WP_000856224.1 DNA polymerase III subunit theta -
NBX04_RS18720 3767979..3768635 + 657 WP_000100250.1 carbon-nitrogen hydrolase family protein -
NBX04_RS18725 3768659..3769357 + 699 WP_000944282.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 3747370..3787654 40284


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T295510 NZ_OW707734:c3765742-3765640 [Salmonella enterica subsp. enterica serovar Typhi]
GCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 144 bp

>AT295510 NZ_OW707734:3765638-3765781 [Salmonella enterica subsp. enterica serovar Typhi]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCTCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References