Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1027667..1027810 Replicon chromosome
Accession NZ_OW706648
Organism Salmonella enterica subsp. enterica serovar Typhi strain BRD948

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1027706..1027808 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1027667..1027810 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NBW98_RS04815 1024091..1024789 - 699 WP_000944282.1 exodeoxyribonuclease X -
NBW98_RS04820 1024813..1025469 - 657 WP_000100250.1 carbon-nitrogen hydrolase family protein -
NBW98_RS04825 1025577..1025807 - 231 WP_000856224.1 DNA polymerase III subunit theta -
NBW98_RS04830 1025945..1026319 + 375 WP_001681742.1 CopC domain-containing protein YobA -
NBW98_RS04835 1026320..1027195 + 876 WP_000979693.1 copper homeostasis membrane protein CopD -
NBW98_RS04840 1027212..1027565 + 354 WP_000722366.1 YebY family protein -
- 1027667..1027810 - 144 - - Antitoxin
- 1027706..1027808 + 103 - - Toxin
NBW98_RS04845 1027929..1028237 - 309 Protein_948 tyrosine-type recombinase/integrase -
NBW98_RS04850 1028236..1028597 - 362 Protein_949 recombinase RecT -
NBW98_RS04855 1028598..1028708 + 111 Protein_950 replication protein -
NBW98_RS04860 1028721..1029116 + 396 Protein_951 DUF977 family protein -
NBW98_RS04865 1029402..1030532 - 1131 WP_000529513.1 GGDEF domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 1022003..1046078 24075


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T295484 NZ_OW706648:1027706-1027808 [Salmonella enterica subsp. enterica serovar Typhi]
GCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 144 bp

>AT295484 NZ_OW706648:c1027810-1027667 [Salmonella enterica subsp. enterica serovar Typhi]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCTCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References