Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2107881..2108544 Replicon chromosome
Accession NC_021500
Organism Enterobacter sp. R4-368

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag H650_RS09925 Protein ID WP_020455134.1
Coordinates 2107881..2108297 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag H650_RS09930 Protein ID WP_020455135.1
Coordinates 2108278..2108544 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H650_RS09905 2103876..2105609 - 1734 WP_020455130.1 single-stranded-DNA-specific exonuclease RecJ -
H650_RS09910 2105615..2106325 - 711 WP_020455131.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
H650_RS09915 2106350..2107246 - 897 WP_020455132.1 site-specific tyrosine recombinase XerD -
H650_RS09920 2107346..2107867 + 522 WP_020455133.1 flavodoxin FldB -
H650_RS09925 2107881..2108297 - 417 WP_020455134.1 protein YgfX Toxin
H650_RS09930 2108278..2108544 - 267 WP_020455135.1 FAD assembly factor SdhE Antitoxin
H650_RS09935 2108791..2109774 + 984 WP_020455136.1 tRNA-modifying protein YgfZ -
H650_RS09940 2109837..2110496 - 660 WP_020455137.1 hemolysin III family protein -
H650_RS09945 2110735..2111463 + 729 WP_044489733.1 MurR/RpiR family transcriptional regulator -
H650_RS09950 2111580..2113013 + 1434 WP_020455139.1 6-phospho-beta-glucosidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16360.26 Da        Isoelectric Point: 11.0079

>T29546 WP_020455134.1 NC_021500:c2108297-2107881 [Enterobacter sp. R4-368]
VVLWQSDLRVSWRAQWISLLLHGLVAAFILFMPWPLSYTPLWLLLLSLVVFDCVRSQRRINACHGEIKLLMDSRLRWQGV
EWDIVGTPWMIRGGMMLRLRRAEDGRRQHLWLAADSMDSQEWRDLRRMITQNPAQGLH

Download         Length: 417 bp

>T29546 NC_021500:c2108297-2107881 [Enterobacter sp. R4-368]
GTGGTCCTGTGGCAATCTGATTTACGCGTCTCATGGCGCGCACAATGGATTTCGTTATTACTGCACGGGCTGGTGGCGGC
GTTCATTCTTTTTATGCCCTGGCCGTTGAGCTATACGCCGCTGTGGCTTTTGCTGCTGTCGCTCGTGGTTTTCGACTGTG
TGCGCAGCCAGCGGCGGATCAACGCCTGCCATGGCGAGATCAAATTGCTGATGGATTCCCGCCTGCGCTGGCAAGGTGTG
GAGTGGGATATTGTCGGTACGCCCTGGATGATCCGCGGTGGCATGATGTTGCGTTTACGCCGTGCGGAAGATGGGCGGCG
CCAGCATTTATGGCTGGCGGCAGACAGTATGGATTCGCAGGAGTGGCGCGATCTACGCCGGATGATCACCCAAAACCCGG
CGCAGGGGCTGCATTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10544.99 Da        Isoelectric Point: 6.3238

>AT29546 WP_020455135.1 NC_021500:c2108544-2108278 [Enterobacter sp. R4-368]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDHDKHLFVRLLESDDPDLFNWLMNHGKPQDAELQRMVQLIQTRN
RDRGPVAI

Download         Length: 267 bp

>AT29546 NC_021500:c2108544-2108278 [Enterobacter sp. R4-368]
ATGGATATTAATAATAAAGCCCGTATCCATTGGGCCTGTCGCCGCGGAATGCGCGAACTCGATATCTCCATCATGCCTTT
TTTCGAACACGAGTACGACTCGCTCAGCGACCATGACAAGCACCTGTTTGTGCGTCTGCTGGAGAGTGATGATCCGGATT
TATTCAACTGGTTGATGAATCATGGCAAACCCCAGGACGCGGAGTTGCAGCGAATGGTGCAGTTAATTCAGACACGGAAT
CGGGATCGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References