Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2302989..2303132 Replicon chromosome
Accession NZ_OW704291
Organism Salmonella enterica subsp. enterica serovar Typhi strain BRD948

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2302991..2303093 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2302989..2303132 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NBX00_RS11485 2300267..2301397 + 1131 WP_000529513.1 GGDEF domain-containing protein -
NBX00_RS11490 2301683..2302078 - 396 Protein_2248 DUF977 family protein -
NBX00_RS11495 2302091..2302201 - 111 Protein_2249 replication protein -
NBX00_RS11500 2302202..2302563 + 362 Protein_2250 recombinase RecT -
NBX00_RS11505 2302562..2302870 + 309 Protein_2251 tyrosine-type recombinase/integrase -
- 2302989..2303132 + 144 - - Antitoxin
- 2302991..2303093 - 103 - - Toxin
NBX00_RS11510 2303234..2303587 - 354 WP_000722366.1 YebY family protein -
NBX00_RS11515 2303604..2304479 - 876 WP_000979693.1 copper homeostasis membrane protein CopD -
NBX00_RS11520 2304480..2304854 - 375 WP_001681742.1 CopC domain-containing protein YobA -
NBX00_RS11525 2304992..2305222 + 231 WP_000856224.1 DNA polymerase III subunit theta -
NBX00_RS11530 2305330..2305986 + 657 WP_000100250.1 carbon-nitrogen hydrolase family protein -
NBX00_RS11535 2306010..2306708 + 699 WP_000944282.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2302396..2308796 6400


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T295443 NZ_OW704291:c2303093-2302991 [Salmonella enterica subsp. enterica serovar Typhi]
GCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 144 bp

>AT295443 NZ_OW704291:2302989-2303132 [Salmonella enterica subsp. enterica serovar Typhi]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCTCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References