Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-pasA/RelE(toxin)
Location 2063427..2063820 Replicon chromosome
Accession NZ_OW703833
Organism Bifidobacterium longum subsp. infantis isolate hadza_2261_Bf14

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NBW67_RS09300 Protein ID WP_229773994.1
Coordinates 2063427..2063654 (-) Length 76 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag NBW67_RS09305 Protein ID WP_250235557.1
Coordinates 2063680..2063820 (-) Length 47 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NBW67_RS09285 2060762..2061484 - 723 WP_250235559.1 hypothetical protein -
NBW67_RS09290 2061549..2062505 - 957 WP_071478049.1 A/G-specific adenine glycosylase -
NBW67_RS09295 2062526..2063188 + 663 WP_003828427.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
NBW67_RS09300 2063427..2063654 - 228 WP_229773994.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NBW67_RS09305 2063680..2063820 - 141 WP_250235557.1 hypothetical protein Antitoxin
NBW67_RS09310 2064499..2065212 - 714 WP_250235555.1 4'-phosphopantetheinyl transferase superfamily protein -
NBW67_RS09315 2065223..2066548 - 1326 WP_250236756.1 MFS transporter -
NBW67_RS09320 2066575..2067762 - 1188 WP_174774172.1 carboxylate--amine ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-72)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 76 a.a.        Molecular weight: 8653.22 Da        Isoelectric Point: 10.1818

>T295438 WP_229773994.1 NZ_OW703833:c2063654-2063427 [Bifidobacterium longum subsp. infantis]
MKKLDRNVAKRIIAKLREISQLEDPRSTGKALAGNLAGLWRYRVGDYRIVCDIEDEVLLILVIDVAHRSKVYKRC

Download         Length: 228 bp

Antitoxin


Download         Length: 47 a.a.        Molecular weight: 5362.92 Da        Isoelectric Point: 3.8345

>AT295438 WP_250235557.1 NZ_OW703833:c2063820-2063680 [Bifidobacterium longum subsp. infantis]
MNEALTESIDRLEYEYGIMKKVEDWRAGRLETATLDELEESLGLED

Download         Length: 141 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References