Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 1495765..1496331 Replicon chromosome
Accession NZ_OW703833
Organism Bifidobacterium longum subsp. infantis isolate hadza_2261_Bf14

Toxin (Protein)


Gene name relE Uniprot ID A0A0L7BQL3
Locus tag NBW67_RS06765 Protein ID WP_029680114.1
Coordinates 1496038..1496331 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NBW67_RS06760 Protein ID WP_143723361.1
Coordinates 1495765..1496034 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NBW67_RS06735 1491516..1492202 - 687 WP_013140734.1 response regulator transcription factor -
NBW67_RS06740 1492334..1492852 + 519 WP_223261719.1 hypothetical protein -
NBW67_RS06745 1492849..1493739 + 891 WP_007056280.1 hypothetical protein -
NBW67_RS06750 1493736..1494414 + 679 Protein_1314 ABC transporter ATP-binding protein -
NBW67_RS06755 1494420..1495580 + 1161 WP_032742829.1 ABC transporter permease -
NBW67_RS06760 1495765..1496034 + 270 WP_143723361.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NBW67_RS06765 1496038..1496331 + 294 WP_029680114.1 type II toxin-antitoxin system YafQ family toxin Toxin
NBW67_RS06770 1496388..1496693 + 306 WP_234883664.1 transporter -
NBW67_RS06775 1497064..1498644 + 1581 WP_143723360.1 amino acid permease -
NBW67_RS06780 1498886..1499125 - 240 WP_014483708.1 hypothetical protein -
NBW67_RS06785 1499422..1499775 + 354 WP_014483707.1 DUF488 domain-containing protein -
NBW67_RS06790 1499841..1500269 - 429 WP_032743755.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-95)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(3-87)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11160.90 Da        Isoelectric Point: 9.7881

>T295435 WP_029680114.1 NZ_OW703833:1496038-1496331 [Bifidobacterium longum subsp. infantis]
MLKPDYTAAFQRDIKKLKRKHADLRPLKEVIRLVLEDTADSKEALRRRHRAHTLTGDLNGVLECHIGNAGDWLLLWIRDD
GTAMFMRTGSHDELLGK

Download         Length: 294 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9860.17 Da        Isoelectric Point: 4.7872

>AT295435 WP_143723361.1 NZ_OW703833:1495765-1496034 [Bifidobacterium longum subsp. infantis]
VSMASVTVRVDADTKQKAANIAEDLGLDLSSVTRAFYKQIVREKRIPLNLSYTTVPPETMEALDEAKNRLADGRPRFNSA
DEMFDSLGI

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0L7BQL3

Antitoxin

Source ID Structure

References