Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/GNAT-DUF1778
Location 55240..56030 Replicon plasmid RHOApf
Accession NZ_OW485607
Organism Rhodovastum atsumiense strain G2-11

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag NBY65_RS33210 Protein ID WP_150043381.1
Coordinates 55240..55743 (-) Length 168 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag NBY65_RS33215 Protein ID WP_150043383.1
Coordinates 55740..56030 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NBY65_RS33190 (RHOA_PF0056) 50920..52278 - 1359 WP_162530765.1 ParB/RepB/Spo0J family partition protein -
NBY65_RS33195 (RHOA_PF0057) 52347..52721 - 375 WP_162530766.1 hypothetical protein -
NBY65_RS33200 (RHOA_PF0058) 53192..53407 - 216 WP_150043377.1 hypothetical protein -
NBY65_RS33205 (RHOA_PF0059) 53632..54951 + 1320 WP_150043379.1 hypothetical protein -
NBY65_RS33210 (RHOA_PF0060) 55240..55743 - 504 WP_150043381.1 GNAT family N-acetyltransferase Toxin
NBY65_RS33215 (RHOA_PF0061) 55740..56030 - 291 WP_150043383.1 DUF1778 domain-containing protein Antitoxin
NBY65_RS33220 56029..56292 + 264 WP_150043385.1 hypothetical protein -
NBY65_RS33225 (RHOA_PF0062) 56483..56953 - 471 WP_150043387.1 hypothetical protein -
NBY65_RS33230 (RHOA_PF0063) 56947..57096 - 150 WP_162530767.1 hypothetical protein -
NBY65_RS33235 (RHOA_PF0064) 57128..57346 - 219 WP_150043389.1 hypothetical protein -
NBY65_RS33240 (RHOA_PF0066) 57826..58215 - 390 WP_150043391.1 hypothetical protein -
NBY65_RS33245 (RHOA_PF0067) 58625..59038 + 414 WP_150043393.1 conjugal transfer protein -
NBY65_RS33250 (RHOA_PF0068) 59585..60508 + 924 WP_239002982.1 tyrosine-type recombinase/integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(22-144)

Antitoxin

Vibrio phage ICP1, Orf50

(10-86)


Sequences

Toxin        


Download         Length: 168 a.a.        Molecular weight: 18559.35 Da        Isoelectric Point: 10.0183

>T295428 WP_150043381.1 NZ_OW485607:c55743-55240 [Rhodovastum atsumiense]
MTRGFRIEKLRRDHAVDGFSCGREELDRFLTRYAFANQQANASQTYLGLHEDAIVGFYSLVVGEVAYDDAPERLTKGLAR
HPVPLMLLARLAVGLAWQGRGIGAGLLKDAIRRTLQAGDIAGIRAFAVHAKDAPARRFYEHFGFVPSPTDPLHLFLLTKD
LRRLVSG

Download         Length: 504 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10690.17 Da        Isoelectric Point: 10.6531

>AT295428 WP_150043383.1 NZ_OW485607:c56030-55740 [Rhodovastum atsumiense]
MASNPPRTSKLDLRLSPEAKARLNAAAHARHQTVSQFVLESALVRADETLAERQRFTLDAARWTAFMTALDAPPRALPRL
ERLFREAGPFDPPEPG

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References