Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapC-ParS/VapC-Xre |
| Location | 99480..100436 | Replicon | plasmid RHOApc |
| Accession | NZ_OW485604 | ||
| Organism | Rhodovastum atsumiense strain G2-11 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | NBY65_RS31320 | Protein ID | WP_250266031.1 |
| Coordinates | 99480..99884 (+) | Length | 135 a.a. |
Antitoxin (Protein)
| Gene name | ParS | Uniprot ID | - |
| Locus tag | NBY65_RS31325 | Protein ID | WP_150045830.1 |
| Coordinates | 99951..100436 (+) | Length | 162 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NBY65_RS31300 (RHOA_PC0113) | 95108..95677 | - | 570 | WP_150045792.1 | recombinase family protein | - |
| NBY65_RS31305 (RHOA_PC0114) | 95842..97416 | + | 1575 | WP_150045793.1 | DUF4158 domain-containing protein | - |
| NBY65_RS31310 (RHOA_PC0115) | 97413..98822 | + | 1410 | WP_239003302.1 | Tn3 family transposase | - |
| NBY65_RS31315 (RHOA_PC0116) | 99257..99478 | + | 222 | WP_150045828.1 | type II toxin-antitoxin system VapB family antitoxin | - |
| NBY65_RS31320 (RHOA_PC0117) | 99480..99884 | + | 405 | WP_250266031.1 | tRNA(fMet)-specific endonuclease VapC | Toxin |
| NBY65_RS31325 (RHOA_PC0118) | 99951..100436 | + | 486 | WP_150045830.1 | DUF2384 domain-containing protein | Antitoxin |
| NBY65_RS31330 (RHOA_PC0119) | 100433..100918 | + | 486 | WP_250266032.1 | RES family NAD+ phosphorylase | - |
| NBY65_RS31335 (RHOA_PC0120) | 101040..102386 | + | 1347 | WP_250266033.1 | HipA domain-containing protein | - |
| NBY65_RS31340 (RHOA_PC0121) | 102373..102672 | + | 300 | WP_250266034.1 | helix-turn-helix domain-containing protein | - |
| NBY65_RS31345 (RHOA_PC0122) | 103188..103358 | + | 171 | WP_162530947.1 | hypothetical protein | - |
| NBY65_RS31350 (RHOA_PC0124) | 103410..103598 | + | 189 | WP_150045873.1 | hypothetical protein | - |
| NBY65_RS31355 (RHOA_PC0125) | 104040..104249 | - | 210 | WP_250265985.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..167269 | 167269 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 135 a.a. Molecular weight: 14989.27 Da Isoelectric Point: 7.1681
>T295426 WP_250266031.1 NZ_OW485604:99480-99884 [Rhodovastum atsumiense]
VLRYMLDTNLCIRVLRDRPPQLRPRFNAEAAALSISTVVLTELFYGAEKSIRPIENRQAVLDFATRLEVLPFDDTAAAHA
AEIRATLERQGQMIGAYDVLIAGHARSRGLIVVTGNLGEFRRVEGLRSEDWLIA
VLRYMLDTNLCIRVLRDRPPQLRPRFNAEAAALSISTVVLTELFYGAEKSIRPIENRQAVLDFATRLEVLPFDDTAAAHA
AEIRATLERQGQMIGAYDVLIAGHARSRGLIVVTGNLGEFRRVEGLRSEDWLIA
Download Length: 405 bp
Antitoxin
Download Length: 162 a.a. Molecular weight: 17245.79 Da Isoelectric Point: 7.0181
>AT295426 WP_150045830.1 NZ_OW485604:99951-100436 [Rhodovastum atsumiense]
MPRAASSVGTIPPSSGTAPAELSYLDVFRPPQERISMIRHGLWATEAKRILAERAIGQGAALKALNMSAATFNKKVKQDL
PLSRDEGERVLGIARLRGQFQAMMEDSGNPEGFDAAAWLSRWLTEPLPSLGGIRPVDLMDTMEGQAVVATALAQIQAGAY
A
MPRAASSVGTIPPSSGTAPAELSYLDVFRPPQERISMIRHGLWATEAKRILAERAIGQGAALKALNMSAATFNKKVKQDL
PLSRDEGERVLGIARLRGQFQAMMEDSGNPEGFDAAAWLSRWLTEPLPSLGGIRPVDLMDTMEGQAVVATALAQIQAGAY
A
Download Length: 486 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|