Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 99257..99884 Replicon plasmid RHOApc
Accession NZ_OW485604
Organism Rhodovastum atsumiense strain G2-11

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NBY65_RS31320 Protein ID WP_250266031.1
Coordinates 99480..99884 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NBY65_RS31315 Protein ID WP_150045828.1
Coordinates 99257..99478 (+) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NBY65_RS31300 (RHOA_PC0113) 95108..95677 - 570 WP_150045792.1 recombinase family protein -
NBY65_RS31305 (RHOA_PC0114) 95842..97416 + 1575 WP_150045793.1 DUF4158 domain-containing protein -
NBY65_RS31310 (RHOA_PC0115) 97413..98822 + 1410 WP_239003302.1 Tn3 family transposase -
NBY65_RS31315 (RHOA_PC0116) 99257..99478 + 222 WP_150045828.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
NBY65_RS31320 (RHOA_PC0117) 99480..99884 + 405 WP_250266031.1 tRNA(fMet)-specific endonuclease VapC Toxin
NBY65_RS31325 (RHOA_PC0118) 99951..100436 + 486 WP_150045830.1 DUF2384 domain-containing protein -
NBY65_RS31330 (RHOA_PC0119) 100433..100918 + 486 WP_250266032.1 RES family NAD+ phosphorylase -
NBY65_RS31335 (RHOA_PC0120) 101040..102386 + 1347 WP_250266033.1 HipA domain-containing protein -
NBY65_RS31340 (RHOA_PC0121) 102373..102672 + 300 WP_250266034.1 helix-turn-helix domain-containing protein -
NBY65_RS31345 (RHOA_PC0122) 103188..103358 + 171 WP_162530947.1 hypothetical protein -
NBY65_RS31350 (RHOA_PC0124) 103410..103598 + 189 WP_150045873.1 hypothetical protein -
NBY65_RS31355 (RHOA_PC0125) 104040..104249 - 210 WP_250265985.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..167269 167269


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-54)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14989.27 Da        Isoelectric Point: 7.1681

>T295425 WP_250266031.1 NZ_OW485604:99480-99884 [Rhodovastum atsumiense]
VLRYMLDTNLCIRVLRDRPPQLRPRFNAEAAALSISTVVLTELFYGAEKSIRPIENRQAVLDFATRLEVLPFDDTAAAHA
AEIRATLERQGQMIGAYDVLIAGHARSRGLIVVTGNLGEFRRVEGLRSEDWLIA

Download         Length: 405 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8171.42 Da        Isoelectric Point: 9.1132

>AT295425 WP_150045828.1 NZ_OW485604:99257-99478 [Rhodovastum atsumiense]
MARTILFQNNRTQAVRLPKDVAFPPGVREVAVLRDGTRRIIVPAGALWDDFFDAPGIDLGERIQPPAQAREIF

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References