Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 119588..120215 Replicon plasmid RHOApb
Accession NZ_OW485603
Organism Rhodovastum atsumiense strain G2-11

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NBY65_RS30565 Protein ID WP_150045829.1
Coordinates 119811..120215 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NBY65_RS30560 Protein ID WP_150045828.1
Coordinates 119588..119809 (+) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NBY65_RS30535 (RHOA_PB0135) 115118..116371 + 1254 WP_250265978.1 DUF1173 family protein -
NBY65_RS30540 (RHOA_PB0137) 116715..117275 + 561 WP_150045848.1 hypothetical protein -
NBY65_RS30545 (RHOA_PB0138) 117331..117720 + 390 WP_250265980.1 hypothetical protein -
NBY65_RS30550 (RHOA_PB0139) 117940..118512 + 573 WP_150045863.1 MbcA/ParS/Xre antitoxin family protein -
NBY65_RS30555 (RHOA_PB0140) 118509..119189 + 681 WP_150045864.1 RES family NAD+ phosphorylase -
NBY65_RS30560 (RHOA_PB0142) 119588..119809 + 222 WP_150045828.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
NBY65_RS30565 (RHOA_PB0143) 119811..120215 + 405 WP_150045829.1 tRNA(fMet)-specific endonuclease VapC Toxin
NBY65_RS30570 (RHOA_PB0144) 120282..120767 + 486 WP_250265981.1 DUF2384 domain-containing protein -
NBY65_RS30575 (RHOA_PB0145) 120764..121249 + 486 WP_250265982.1 RES family NAD+ phosphorylase -
NBY65_RS30580 (RHOA_PB0146) 121371..122717 + 1347 WP_250265983.1 HipA domain-containing protein -
NBY65_RS30585 (RHOA_PB0147) 122704..123003 + 300 WP_250265984.1 helix-turn-helix domain-containing protein -
NBY65_RS30590 (RHOA_PB0148) 123519..123689 + 171 WP_162530950.1 hypothetical protein -
NBY65_RS30595 (RHOA_PB0150) 124380..124589 - 210 WP_250265985.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..199245 199245


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-54)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 15047.31 Da        Isoelectric Point: 6.4729

>T295422 WP_150045829.1 NZ_OW485603:119811-120215 [Rhodovastum atsumiense]
VLRYMLDTNLCIRVLRDRPPQLRPRFNAEAAALSISTVVLTELFYGAEKSIRPIENRQAVLDFATRLEVLPFDDTAAAHA
AEIRATLERQGQMIGAYDVLIAGHARSRGLIVVTGNLDEFRRVEGLRSEDWLIA

Download         Length: 405 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8171.42 Da        Isoelectric Point: 9.1132

>AT295422 WP_150045828.1 NZ_OW485603:119588-119809 [Rhodovastum atsumiense]
MARTILFQNNRTQAVRLPKDVAFPPGVREVAVLRDGTRRIIVPAGALWDDFFDAPGIDLGERIQPPAQAREIF

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References