Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/RelE-RelB |
| Location | 344476..345035 | Replicon | chromosome |
| Accession | NZ_OW443151 | ||
| Organism | Vibrio cholerae strain CNRVC190247 isolate YE-NCPHL-18035-PI | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | D2YI11 |
| Locus tag | OC536_RS15780 | Protein ID | WP_000578473.1 |
| Coordinates | 344476..344754 (-) | Length | 93 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | OC536_RS15785 | Protein ID | WP_000381186.1 |
| Coordinates | 344751..345035 (-) | Length | 95 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OC536_RS15730 (CNRVC190247_03149) | 340313..341050 | + | 738 | WP_032477355.1 | SDR family oxidoreductase | - |
| OC536_RS15735 | 341028..341165 | + | 138 | WP_113707170.1 | DUF3265 domain-containing protein | - |
| OC536_RS15740 | 341377..341530 | + | 154 | Protein_312 | DUF645 family protein | - |
| OC536_RS15745 (CNRVC190247_03150) | 341728..342048 | + | 321 | WP_000248687.1 | DUF4144 domain-containing protein | - |
| OC536_RS15750 (CNRVC190247_03151) | 342275..342469 | + | 195 | WP_000526238.1 | hypothetical protein | - |
| OC536_RS15755 | 342502..342597 | + | 96 | WP_075042587.1 | DUF3265 domain-containing protein | - |
| OC536_RS15760 (CNRVC190247_03152) | 342605..342922 | - | 318 | WP_000077449.1 | CcdB family protein | - |
| OC536_RS15765 (CNRVC190247_03153) | 342922..343167 | - | 246 | WP_001260801.1 | type II toxin-antitoxin system CcdA family antitoxin | - |
| OC536_RS15770 (CNRVC190247_03154) | 343347..343802 | + | 456 | Protein_318 | GNAT family N-acetyltransferase | - |
| OC536_RS15775 (CNRVC190247_03155) | 343949..344308 | + | 360 | WP_000609948.1 | HNH endonuclease signature motif containing protein | - |
| OC536_RS15780 (CNRVC190247_03156) | 344476..344754 | - | 279 | WP_000578473.1 | type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family | Toxin |
| OC536_RS15785 (CNRVC190247_03157) | 344751..345035 | - | 285 | WP_000381186.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| OC536_RS15790 | 345647..345853 | + | 207 | WP_080284769.1 | DUF3709 domain-containing protein | - |
| OC536_RS15795 (CNRVC190247_03158) | 346170..346562 | + | 393 | WP_001085003.1 | nuclear transport factor 2 family protein | - |
| OC536_RS15800 (CNRVC190247_03159) | 346702..346989 | + | 288 | WP_032477325.1 | hypothetical protein | - |
| OC536_RS15805 | 347492..347560 | + | 69 | Protein_325 | acetyltransferase | - |
| OC536_RS15810 | 347739..347909 | + | 171 | WP_080284771.1 | DUF645 family protein | - |
| OC536_RS15815 (CNRVC190247_03161) | 348108..348386 | - | 279 | WP_000578475.1 | type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family | - |
| OC536_RS15820 (CNRVC190247_03162) | 348383..348667 | - | 285 | WP_000381183.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | - |
| OC536_RS15825 | 348783..348926 | + | 144 | WP_080284772.1 | acetyltransferase | - |
| OC536_RS15830 | 349026..349202 | + | 177 | WP_001891218.1 | DUF645 family protein | - |
| OC536_RS15835 | 349583..349736 | + | 154 | Protein_331 | DUF645 family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | qnrVC4 | - | 308122..375907 | 67785 | |
| - | inside | Integron | qnrVC4 | - | 308793..373362 | 64569 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|