Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-dinJ/YafQ-RelB
Location 566085..566616 Replicon chromosome
Accession NZ_OW370493
Organism Rickettsia endosymbiont of Oedothorax gibbosus strain Oegibbosus-W744x776

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NBW66_RS03165 Protein ID WP_250311722.1
Coordinates 566085..566366 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag NBW66_RS03170 Protein ID WP_250311723.1
Coordinates 566353..566616 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NBW66_RS03135 561606..562859 - 1254 WP_250311720.1 IS66 family transposase -
NBW66_RS03140 562897..563247 - 351 WP_250311006.1 IS66 family insertion sequence element accessory protein TnpB -
NBW66_RS03145 563241..563594 - 354 WP_250311719.1 transposase -
NBW66_RS03150 563668..564240 + 573 WP_284346803.1 IS110 family transposase -
NBW66_RS03155 564331..565221 + 891 WP_250310582.1 IS982 family transposase -
NBW66_RS03160 565316..565486 + 171 WP_250311721.1 hypothetical protein -
NBW66_RS03165 566085..566366 - 282 WP_250311722.1 type II toxin-antitoxin system YafQ family toxin Toxin
NBW66_RS03170 566353..566616 - 264 WP_250311723.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NBW66_RS03175 567217..567849 + 633 WP_250311724.1 DUF4065 domain-containing protein -
NBW66_RS03180 567827..568096 + 270 WP_250311725.1 Txe/YoeB family addiction module toxin -
NBW66_RS03185 568642..569478 + 837 WP_250311726.1 hypothetical protein -
NBW66_RS03190 569509..570048 + 540 WP_250311727.1 hypothetical protein -
NBW66_RS03195 570032..570493 + 462 WP_250311728.1 lysozyme -
NBW66_RS03200 570634..571131 + 498 WP_250311729.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-70)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11011.76 Da        Isoelectric Point: 9.1846

>T295382 WP_250311722.1 NZ_OW370493:c566366-566085 [Rickettsia endosymbiont of Oedothorax gibbosus]
MRTIKRTTQFKRDYTREKRRQHGVTLDNDLSKAIELLVIDAQLPKCMREHPLIGDWKDCRDCHIKSDLVLIYQKSDDYTL
KLIRLGSHSELSL

Download         Length: 282 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9437.98 Da        Isoelectric Point: 8.7872

>AT295382 WP_250311723.1 NZ_OW370493:c566616-566353 [Rickettsia endosymbiont of Oedothorax gibbosus]
MAVNTTVRARIDENIKEEASIVLSTMGLTVSDAFRMLLTRIAREKALPFDPLVPNAKTIEAIKAARSGKLITIGSINNLL
TDLNAND

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References