Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA-HicB
Location 5559157..5559776 Replicon
Accession NC_021499
Organism Pseudomonas resinovorans NBRC 106553

Toxin (Protein)


Gene name hicA Uniprot ID S6B0J5
Locus tag PCA10_RS25015 Protein ID WP_016494879.1
Coordinates 5559594..5559776 (-) Length 61 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag PCA10_RS25010 Protein ID WP_041770442.1
Coordinates 5559157..5559564 (-) Length 136 a.a.

Genomic Context

PCA10_RS24990PCA10_RS24995PCA10_RS25000PCA10_RS25005PCA10_RS25020PCA10_RS25025PCA10_RS25030PCA10_RS25035PCA10_RS25010PCA10_RS25015PCA10_RS25040PCA10_RS25045
Location: 5555909..5556745 (837 bp)
Type: Others
Protein ID: WP_016494874.1
Location: 5556857..5557612 (756 bp)
Type: Others
Protein ID: WP_041770441.1
Location: 5558116..5558568 (453 bp)
Type: Others
Protein ID: WP_016494876.1
Location: 5558701..5559042 (342 bp)
Type: Others
Protein ID: WP_016494877.1
Location: 5559910..5560704 (795 bp)
Type: Others
Protein ID: WP_016494880.1
Location: 5561083..5561532 (450 bp)
Type: Others
Protein ID: WP_016494881.1
Location: 5561642..5562175 (534 bp)
Type: Others
Protein ID: WP_016494882.1
Location: 5562312..5562716 (405 bp)
Type: Others
Protein ID: WP_016494883.1
Location: 5559157..5559564 (408 bp)
Type: Antitoxin
Protein ID: WP_041770442.1
Location: 5559594..5559776 (183 bp)
Type: Toxin
Protein ID: WP_016494879.1
Location: 5562777..5564273 (1497 bp)
Type: Others
Protein ID: WP_016494884.1
Location: 5564381..5564668 (288 bp)
Type: Others
Protein ID: WP_016494885.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PCA10_RS249905555909..5556745+837WP_016494874.1arylamine N-acetyltransferase-
PCA10_RS249955556857..5557612+756WP_041770441.1phytanoyl-CoA dioxygenase family protein-
PCA10_RS250005558116..5558568+453WP_016494876.1LEA type 2 family protein-
PCA10_RS250055558701..5559042+342WP_016494877.1alkylphosphonate utilization protein-
PCA10_RS250105559157..5559564-408WP_041770442.1type II toxin-antitoxin system HicB family antitoxinAntitoxin
PCA10_RS250155559594..5559776-183WP_016494879.1type II toxin-antitoxin system HicA family toxinToxin
PCA10_RS250205559910..5560704+795WP_016494880.1NYN domain-containing protein-
PCA10_RS250255561083..5561532+450WP_016494881.1Bro-N domain-containing protein-
PCA10_RS250305561642..5562175+534WP_016494882.1transposase-
PCA10_RS250355562312..5562716+405WP_016494883.1hypothetical protein-
PCA10_RS250405562777..5564273-1497WP_016494884.1CoA-acylating methylmalonate-semialdehyde dehydrogenase-
PCA10_RS250455564381..5564668-288WP_016494885.1cupin domain-containing protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(4-59)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(3-128)


Sequences

Toxin        


Download         Length: 61 a.a.        Molecular weight: 6757.96 Da        Isoelectric Point: 11.3688

>T29535 WP_016494879.1 NC_021499:c5559776-5559594 [Pseudomonas resinovorans NBRC 106553]
VNSRQLMELIEADGWFLVRVRGSHHHFKHPSKPGLVTIPHPKKDLLPRTAASILKQAGLK

Download         Length: 183 bp

>T29535 NC_021499:c5559776-5559594 [Pseudomonas resinovorans NBRC 106553]
GTGAACAGTCGACAACTCATGGAGCTGATCGAGGCCGATGGATGGTTTCTGGTCAGGGTCAGGGGCAGTCATCACCACTT
CAAGCACCCGAGCAAGCCGGGCCTGGTGACGATTCCCCATCCGAAGAAAGACCTGCTGCCCAGGACGGCGGCCAGCATCC
TCAAACAGGCAGGGCTCAAATGA

Antitoxin


Download         Length: 136 a.a.        Molecular weight: 14721.75 Da        Isoelectric Point: 4.4268

>AT29535 WP_041770442.1 NC_021499:c5559564-5559157 [Pseudomonas resinovorans NBRC 106553]
MLYPIAILPGDDGHAWGVEVPDLPGCFSAGDDLDDAMAMAREAIEGHLELLAEEGAPIPVARKVTFHAANPEYTGCTWAL
VEIDVTRYMGKAEKLNITLPGYLLNRIDEYVRSHPEQKSRSGFLAAAALRVLQES

Download         Length: 408 bp

>AT29535 NC_021499:c5559564-5559157 [Pseudomonas resinovorans NBRC 106553]
ATGCTCTACCCGATAGCGATTCTCCCCGGCGACGATGGGCATGCCTGGGGCGTGGAGGTGCCAGACTTGCCGGGCTGCTT
CTCGGCCGGAGATGATCTGGACGATGCGATGGCCATGGCGCGCGAGGCCATCGAGGGGCATCTGGAGTTGCTGGCGGAGG
AGGGTGCGCCGATTCCGGTGGCGAGGAAGGTGACCTTCCATGCGGCGAATCCCGAATACACCGGCTGCACCTGGGCCCTG
GTGGAGATCGACGTGACCCGCTACATGGGCAAGGCGGAGAAGCTGAACATCACCCTGCCGGGCTACCTGCTCAATCGCAT
CGATGAGTACGTGCGCAGCCACCCGGAGCAGAAGAGCCGTTCGGGCTTCCTGGCCGCGGCGGCGTTGCGGGTGTTGCAGG
AGTCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBS6B0J5

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References