Detailed information of TA system TA029534

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-stbD/ParE(toxin)
• Location: 5337979..5338537
• Accession: NC_021499
• Organism: Pseudomonas resinovorans NBRC 106553

Toxin (Protein)

• Gene name: relE
• Uniprot ID: S6ANL4
• Locus tag: PCA10_RS24080
• Protein ID: WP_016494703.1
• Coordinates: 5337979..5338269 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: stbD
• Uniprot ID: -
• Locus tag: PCA10_RS24085
• Protein ID: WP_016494704.1
• Coordinates: 5338262..5338537 (-)
• Length: 92 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PCA10_RS24045	5333724..5334014	-	291	WP_016494695.1	excalibur calcium-binding domain-containing protein	-
PCA10_RS24050	5334054..5334359	-	306	WP_016494696.1	HigA family addiction module antidote protein	-
PCA10_RS24055	5334447..5335022	-	576	WP_016494697.1	hypothetical protein	-
PCA10_RS30495	5335353..5335625	-	273	WP_144277003.1	DNA-binding protein	-
PCA10_RS24060	5335740..5335970	+	231	WP_016494699.1	hypothetical protein	-
PCA10_RS24065	5336022..5336171	-	150	WP_016494700.1	type II toxin-antitoxin system RelE/ParE family toxin	-
PCA10_RS24070	5336528..5337397	-	870	WP_016494701.1	restriction endonuclease	-
PCA10_RS24075	5337582..5337890	+	309	WP_144277071.1	hypothetical protein	-
PCA10_RS24080	5337979..5338269	-	291	WP_016494703.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
PCA10_RS24085	5338262..5338537	-	276	WP_016494704.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
PCA10_RS24090	5339042..5339269	+	228	WP_016494705.1	hypothetical protein	-
PCA10_RS24095	5339395..5340306	-	912	WP_016494706.1	DMT family transporter	-
PCA10_RS24100	5340310..5340954	-	645	WP_016494707.1	carbonate dehydratase	-
PCA10_RS24105	5341025..5341477	-	453	WP_016494708.1	ribosomal protein S18-alanine N-acetyltransferase	-
PCA10_RS24110	5341474..5342274	-	801	WP_041770429.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (7-84)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 11336.29 Da
• Isoelectric Point: 10.5041

>T29534 WP_016494703.1 NC_021499:c5338269-5337979 [Pseudomonas resinovorans NBRC 106553]
VPRFNLEFNVKALKEWNKLDSTIRLQFAKKLKERLDLPRVESDRLKGLPDCYKIKLRSVGYRLVYEVVDQRLVVTVIAVG
KRERSEVYDSAKKRVD

Nucleotide

• Length: 291 bp

>T29534 NC_021499:c5338269-5337979 [Pseudomonas resinovorans NBRC 106553]
GTGCCTAGGTTCAACCTGGAGTTCAACGTTAAGGCGCTCAAGGAGTGGAACAAGCTGGACTCCACTATCCGGCTCCAGTT
CGCCAAGAAGCTGAAGGAGCGCCTCGACTTGCCCCGAGTCGAATCCGACCGGCTCAAAGGCTTGCCGGACTGCTACAAGA
TCAAGCTGCGTTCGGTGGGCTACCGCCTCGTCTATGAGGTGGTGGACCAGCGCCTAGTTGTCACCGTGATTGCAGTGGGC
AAGCGTGAGCGTTCAGAGGTCTATGACAGCGCCAAGAAACGGGTTGATTAG

Antitoxin

Protein

• Length: 92 a.a.
• Molecular weight: 9963.33 Da
• Isoelectric Point: 4.1353

>AT29534 WP_016494704.1 NC_021499:c5338537-5338262 [Pseudomonas resinovorans NBRC 106553]
MPFQILADVAASVTDLKRDPMGTIREGHGETVVILNRNEPAFYAVPPARYEAMLELIEDLRLAELVRARQGEPTVAVDID
DLIAQATDTSA

Nucleotide

• Length: 276 bp

>AT29534 NC_021499:c5338537-5338262 [Pseudomonas resinovorans NBRC 106553]
ATGCCTTTCCAAATTTTGGCGGATGTAGCCGCCTCCGTGACTGACCTCAAGCGTGACCCGATGGGCACCATCCGTGAAGG
TCATGGCGAAACCGTCGTTATCCTCAACCGCAATGAGCCGGCCTTCTATGCCGTTCCGCCTGCGCGTTACGAGGCGATGC
TTGAGCTGATCGAGGATCTGCGTCTGGCCGAACTGGTCCGCGCTCGCCAGGGAGAACCGACCGTAGCTGTGGACATTGAC
GATCTGATCGCTCAGGCGACCGATACCAGTGCCTAG

Structures

Toxin

• AlphaFold DB: S6ANL4