Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 1667923..1669618 Replicon
Accession NC_021499
Organism Pseudomonas resinovorans NBRC 106553

Toxin (Protein)


Gene name doc Uniprot ID S6AGP3
Locus tag PCA10_RS07715 Protein ID WP_016491492.1
Coordinates 1667923..1668792 (+) Length 290 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID S6AT22
Locus tag PCA10_RS07720 Protein ID WP_016491493.1
Coordinates 1668785..1669618 (+) Length 278 a.a.

Genomic Context

PCA10_RS07690PCA10_RS07695PCA10_RS07700PCA10_RS07705PCA10_RS07710PCA10_RS07715PCA10_RS07720PCA10_RS07725PCA10_RS07730PCA10_RS07735PCA10_RS07740
Location: 1663929..1664780 (852 bp)
Type: Others
Protein ID: WP_081663920.1
Location: 1664818..1665813 (996 bp)
Type: Others
Protein ID: WP_016491488.1
Location: 1665823..1666599 (777 bp)
Type: Others
Protein ID: WP_016491489.1
Location: 1666605..1667366 (762 bp)
Type: Others
Protein ID: WP_016491490.1
Location: 1667378..1667914 (537 bp)
Type: Others
Protein ID: WP_016491491.1
Location: 1667923..1668792 (870 bp)
Type: Toxin
Protein ID: WP_016491492.1
Location: 1668785..1669618 (834 bp)
Type: Antitoxin
Protein ID: WP_016491493.1
Location: 1669605..1670402 (798 bp)
Type: Others
Protein ID: WP_016491494.1
Location: 1670395..1672077 (1683 bp)
Type: Others
Protein ID: WP_016491495.1
Location: 1672088..1672891 (804 bp)
Type: Others
Protein ID: WP_016491496.1
Location: 1672902..1674386 (1485 bp)
Type: Others
Protein ID: WP_016491497.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PCA10_RS076901663929..1664780+852WP_081663920.1ABC transporter ATP-binding protein-
PCA10_RS076951664818..1665813+996WP_016491488.1ABC transporter substrate-binding protein-
PCA10_RS077001665823..1666599+777WP_016491489.1ABC transporter permease-
PCA10_RS077051666605..1667366+762WP_016491490.1SDR family oxidoreductase-
PCA10_RS077101667378..1667914+537WP_016491491.1cupin domain-containing protein-
PCA10_RS077151667923..1668792+870WP_016491492.1alpha/beta hydrolaseToxin
PCA10_RS077201668785..1669618+834WP_016491493.1IclR family transcriptional regulatorAntitoxin
PCA10_RS077251669605..1670402+798WP_016491494.1SDR family oxidoreductase-
PCA10_RS077301670395..1672077+1683WP_016491495.1thiamine pyrophosphate-binding protein-
PCA10_RS077351672088..1672891+804WP_016491496.1aspartate dehydrogenase-
PCA10_RS077401672902..1674386+1485WP_016491497.1aldehyde dehydrogenase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(41-272)

Antitoxin

Transcription regulator IclR, C-terminal

(130-253)


Sequences

Toxin        


Download         Length: 290 a.a.        Molecular weight: 30444.83 Da        Isoelectric Point: 7.3626

>T29532 WP_016491492.1 NC_021499:1667923-1668792 [Pseudomonas resinovorans NBRC 106553]
MNMAQTRIPAPSLPQSFPERLVQLADGAQVAIRECGQGPAVVLLHGIGSGSASWLHCAQRLAASCRVIAWDAPGYGQSTP
LPQAQPRAGDYAARLELLLAELGVERCLLVGHSLGALMATAYASGVGAARVGRLLLISPARGYGAPELRDSGLRVRQQRL
DNLERLGIDGLASERTARLLGPNPSEGALAWVRWNMARLNPHGYRQAVELLCGDDLLAYGVPAMPCEVHCGEADGITPPQ
NCSAIARLLDAPFSMIPGAGHASPIEQPEVVAGRIGHAQRHSFQGTANG

Download         Length: 870 bp

>T29532 NC_021499:1667923-1668792 [Pseudomonas resinovorans NBRC 106553]
ATGAACATGGCGCAGACCCGCATCCCCGCCCCCAGCCTGCCGCAGAGCTTCCCCGAGCGCCTGGTGCAACTCGCCGACGG
CGCCCAGGTGGCGATCCGCGAGTGCGGCCAGGGCCCCGCCGTGGTGCTGTTGCACGGCATAGGCTCCGGTTCGGCGTCCT
GGCTGCATTGCGCCCAGCGCCTGGCCGCGAGCTGCCGGGTGATCGCCTGGGACGCACCCGGCTACGGGCAATCCACACCG
CTGCCGCAGGCGCAGCCCAGGGCCGGTGACTACGCCGCGCGACTGGAGCTGCTGCTGGCGGAACTGGGGGTGGAGCGCTG
CCTGCTGGTCGGGCATTCGCTCGGCGCGCTGATGGCCACGGCCTATGCCAGTGGCGTCGGCGCGGCGCGGGTCGGCCGCC
TGCTGCTGATCAGCCCGGCACGCGGCTACGGCGCGCCGGAACTGCGTGACAGCGGCCTGCGGGTGCGCCAGCAACGCCTG
GACAACCTCGAGCGCCTGGGCATCGACGGCCTGGCCAGCGAGCGCACCGCACGCCTGCTGGGCCCCAACCCCAGCGAGGG
CGCCCTGGCCTGGGTGCGCTGGAACATGGCGCGGCTCAACCCGCACGGCTACCGCCAGGCCGTCGAGTTGCTCTGCGGCG
ACGACCTGCTGGCCTACGGCGTGCCCGCCATGCCCTGCGAAGTGCACTGCGGCGAAGCCGACGGCATTACCCCGCCGCAG
AACTGCAGCGCCATCGCTCGTTTGCTCGACGCGCCGTTCTCGATGATTCCCGGGGCCGGCCATGCCAGCCCCATCGAACA
ACCCGAAGTGGTAGCAGGACGCATCGGCCACGCACAACGCCACTCTTTCCAAGGAACCGCCAATGGATAA

Antitoxin


Download         Length: 278 a.a.        Molecular weight: 30771.15 Da        Isoelectric Point: 6.6069

>AT29532 WP_016491493.1 NC_021499:1668785-1669618 [Pseudomonas resinovorans NBRC 106553]
MDKPDDPQDKYIVPGLERGLLLLCEFSRKNRTLSAPELARRLKLPRSTIFRLLTTLETMGFVTRNGNEYRLGMAVLRLGF
EYLASLELTELGQPLLNQLCDDIRYPCNLVVRDGRSIVYVAKVSPSTLLTSTVNVGTRLPAHATVLGRILLQDLSLGELR
DLYPEEHLESYSPNTPRTVLELFNLLQSDRLRGFVQGEGFFESTISTVAAPVRDHSGKVVAAMGATIPSGHIEPNSIDNL
VSTVRASADQLSHLLNYAPDSHDNVTSIFRSKQHESV

Download         Length: 834 bp

>AT29532 NC_021499:1668785-1669618 [Pseudomonas resinovorans NBRC 106553]
ATGGATAAGCCAGACGATCCGCAAGACAAGTACATAGTGCCCGGCCTGGAGCGCGGCCTGCTGCTGCTCTGCGAGTTCAG
CCGGAAGAACCGTACCCTGTCGGCACCGGAGCTGGCGCGGCGCCTGAAGCTGCCGCGCTCGACCATCTTCCGCCTGCTGA
CCACCCTGGAAACCATGGGCTTCGTCACCCGCAACGGCAACGAGTACCGCCTGGGCATGGCGGTGCTGCGTCTGGGCTTC
GAGTACCTGGCCTCGCTGGAACTGACCGAACTCGGCCAGCCGCTGCTGAACCAGCTGTGCGACGACATCCGCTACCCCTG
CAACCTGGTGGTACGCGATGGCCGCTCCATCGTCTACGTGGCCAAGGTCTCGCCCTCCACCTTGCTGACCAGCACGGTCA
ACGTCGGCACCCGCCTGCCGGCCCACGCCACCGTGCTCGGCCGCATCCTCCTGCAGGACCTGTCGCTGGGCGAGCTGCGC
GACCTGTACCCGGAAGAACACCTGGAAAGCTACTCGCCGAACACCCCGCGTACCGTGCTGGAGCTGTTCAACCTGCTGCA
GAGCGATCGCCTGCGCGGCTTCGTCCAGGGCGAGGGCTTCTTCGAGTCGACCATCTCCACCGTGGCCGCGCCGGTGCGCG
ACCACAGCGGCAAGGTGGTGGCCGCCATGGGCGCCACCATCCCCTCGGGGCACATCGAGCCGAACAGCATCGACAACCTG
GTGAGCACCGTGCGCGCCAGCGCCGACCAGCTGTCGCACCTGCTCAACTACGCCCCGGACAGCCACGACAACGTCACCTC
CATCTTCCGGAGCAAGCAGCATGAGTCTGTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBS6AGP3

Antitoxin

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Source
ID
Structure
AlphaFold DBS6AT22

References