Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | phd-doc/HTH_IclR(antitoxin) |
Location | 1667923..1669618 | Replicon | |
Accession | NC_021499 | ||
Organism | Pseudomonas resinovorans NBRC 106553 |
Toxin (Protein)
Gene name | doc | Uniprot ID | S6AGP3 |
Locus tag | PCA10_RS07715 | Protein ID | WP_016491492.1 |
Coordinates | 1667923..1668792 (+) | Length | 290 a.a. |
Antitoxin (Protein)
Gene name | phd | Uniprot ID | S6AT22 |
Locus tag | PCA10_RS07720 | Protein ID | WP_016491493.1 |
Coordinates | 1668785..1669618 (+) | Length | 278 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PCA10_RS07690 | 1663929..1664780 | + | 852 | WP_081663920.1 | ABC transporter ATP-binding protein | - |
PCA10_RS07695 | 1664818..1665813 | + | 996 | WP_016491488.1 | ABC transporter substrate-binding protein | - |
PCA10_RS07700 | 1665823..1666599 | + | 777 | WP_016491489.1 | ABC transporter permease | - |
PCA10_RS07705 | 1666605..1667366 | + | 762 | WP_016491490.1 | SDR family oxidoreductase | - |
PCA10_RS07710 | 1667378..1667914 | + | 537 | WP_016491491.1 | cupin domain-containing protein | - |
PCA10_RS07715 | 1667923..1668792 | + | 870 | WP_016491492.1 | alpha/beta hydrolase | Toxin |
PCA10_RS07720 | 1668785..1669618 | + | 834 | WP_016491493.1 | IclR family transcriptional regulator | Antitoxin |
PCA10_RS07725 | 1669605..1670402 | + | 798 | WP_016491494.1 | SDR family oxidoreductase | - |
PCA10_RS07730 | 1670395..1672077 | + | 1683 | WP_016491495.1 | thiamine pyrophosphate-binding protein | - |
PCA10_RS07735 | 1672088..1672891 | + | 804 | WP_016491496.1 | aspartate dehydrogenase | - |
PCA10_RS07740 | 1672902..1674386 | + | 1485 | WP_016491497.1 | aldehyde dehydrogenase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 290 a.a. Molecular weight: 30444.83 Da Isoelectric Point: 7.3626
>T29532 WP_016491492.1 NC_021499:1667923-1668792 [Pseudomonas resinovorans NBRC 106553]
MNMAQTRIPAPSLPQSFPERLVQLADGAQVAIRECGQGPAVVLLHGIGSGSASWLHCAQRLAASCRVIAWDAPGYGQSTP
LPQAQPRAGDYAARLELLLAELGVERCLLVGHSLGALMATAYASGVGAARVGRLLLISPARGYGAPELRDSGLRVRQQRL
DNLERLGIDGLASERTARLLGPNPSEGALAWVRWNMARLNPHGYRQAVELLCGDDLLAYGVPAMPCEVHCGEADGITPPQ
NCSAIARLLDAPFSMIPGAGHASPIEQPEVVAGRIGHAQRHSFQGTANG
MNMAQTRIPAPSLPQSFPERLVQLADGAQVAIRECGQGPAVVLLHGIGSGSASWLHCAQRLAASCRVIAWDAPGYGQSTP
LPQAQPRAGDYAARLELLLAELGVERCLLVGHSLGALMATAYASGVGAARVGRLLLISPARGYGAPELRDSGLRVRQQRL
DNLERLGIDGLASERTARLLGPNPSEGALAWVRWNMARLNPHGYRQAVELLCGDDLLAYGVPAMPCEVHCGEADGITPPQ
NCSAIARLLDAPFSMIPGAGHASPIEQPEVVAGRIGHAQRHSFQGTANG
Download Length: 870 bp
>T29532 NC_021499:1667923-1668792 [Pseudomonas resinovorans NBRC 106553]
ATGAACATGGCGCAGACCCGCATCCCCGCCCCCAGCCTGCCGCAGAGCTTCCCCGAGCGCCTGGTGCAACTCGCCGACGG
CGCCCAGGTGGCGATCCGCGAGTGCGGCCAGGGCCCCGCCGTGGTGCTGTTGCACGGCATAGGCTCCGGTTCGGCGTCCT
GGCTGCATTGCGCCCAGCGCCTGGCCGCGAGCTGCCGGGTGATCGCCTGGGACGCACCCGGCTACGGGCAATCCACACCG
CTGCCGCAGGCGCAGCCCAGGGCCGGTGACTACGCCGCGCGACTGGAGCTGCTGCTGGCGGAACTGGGGGTGGAGCGCTG
CCTGCTGGTCGGGCATTCGCTCGGCGCGCTGATGGCCACGGCCTATGCCAGTGGCGTCGGCGCGGCGCGGGTCGGCCGCC
TGCTGCTGATCAGCCCGGCACGCGGCTACGGCGCGCCGGAACTGCGTGACAGCGGCCTGCGGGTGCGCCAGCAACGCCTG
GACAACCTCGAGCGCCTGGGCATCGACGGCCTGGCCAGCGAGCGCACCGCACGCCTGCTGGGCCCCAACCCCAGCGAGGG
CGCCCTGGCCTGGGTGCGCTGGAACATGGCGCGGCTCAACCCGCACGGCTACCGCCAGGCCGTCGAGTTGCTCTGCGGCG
ACGACCTGCTGGCCTACGGCGTGCCCGCCATGCCCTGCGAAGTGCACTGCGGCGAAGCCGACGGCATTACCCCGCCGCAG
AACTGCAGCGCCATCGCTCGTTTGCTCGACGCGCCGTTCTCGATGATTCCCGGGGCCGGCCATGCCAGCCCCATCGAACA
ACCCGAAGTGGTAGCAGGACGCATCGGCCACGCACAACGCCACTCTTTCCAAGGAACCGCCAATGGATAA
ATGAACATGGCGCAGACCCGCATCCCCGCCCCCAGCCTGCCGCAGAGCTTCCCCGAGCGCCTGGTGCAACTCGCCGACGG
CGCCCAGGTGGCGATCCGCGAGTGCGGCCAGGGCCCCGCCGTGGTGCTGTTGCACGGCATAGGCTCCGGTTCGGCGTCCT
GGCTGCATTGCGCCCAGCGCCTGGCCGCGAGCTGCCGGGTGATCGCCTGGGACGCACCCGGCTACGGGCAATCCACACCG
CTGCCGCAGGCGCAGCCCAGGGCCGGTGACTACGCCGCGCGACTGGAGCTGCTGCTGGCGGAACTGGGGGTGGAGCGCTG
CCTGCTGGTCGGGCATTCGCTCGGCGCGCTGATGGCCACGGCCTATGCCAGTGGCGTCGGCGCGGCGCGGGTCGGCCGCC
TGCTGCTGATCAGCCCGGCACGCGGCTACGGCGCGCCGGAACTGCGTGACAGCGGCCTGCGGGTGCGCCAGCAACGCCTG
GACAACCTCGAGCGCCTGGGCATCGACGGCCTGGCCAGCGAGCGCACCGCACGCCTGCTGGGCCCCAACCCCAGCGAGGG
CGCCCTGGCCTGGGTGCGCTGGAACATGGCGCGGCTCAACCCGCACGGCTACCGCCAGGCCGTCGAGTTGCTCTGCGGCG
ACGACCTGCTGGCCTACGGCGTGCCCGCCATGCCCTGCGAAGTGCACTGCGGCGAAGCCGACGGCATTACCCCGCCGCAG
AACTGCAGCGCCATCGCTCGTTTGCTCGACGCGCCGTTCTCGATGATTCCCGGGGCCGGCCATGCCAGCCCCATCGAACA
ACCCGAAGTGGTAGCAGGACGCATCGGCCACGCACAACGCCACTCTTTCCAAGGAACCGCCAATGGATAA
Antitoxin
Download Length: 278 a.a. Molecular weight: 30771.15 Da Isoelectric Point: 6.6069
>AT29532 WP_016491493.1 NC_021499:1668785-1669618 [Pseudomonas resinovorans NBRC 106553]
MDKPDDPQDKYIVPGLERGLLLLCEFSRKNRTLSAPELARRLKLPRSTIFRLLTTLETMGFVTRNGNEYRLGMAVLRLGF
EYLASLELTELGQPLLNQLCDDIRYPCNLVVRDGRSIVYVAKVSPSTLLTSTVNVGTRLPAHATVLGRILLQDLSLGELR
DLYPEEHLESYSPNTPRTVLELFNLLQSDRLRGFVQGEGFFESTISTVAAPVRDHSGKVVAAMGATIPSGHIEPNSIDNL
VSTVRASADQLSHLLNYAPDSHDNVTSIFRSKQHESV
MDKPDDPQDKYIVPGLERGLLLLCEFSRKNRTLSAPELARRLKLPRSTIFRLLTTLETMGFVTRNGNEYRLGMAVLRLGF
EYLASLELTELGQPLLNQLCDDIRYPCNLVVRDGRSIVYVAKVSPSTLLTSTVNVGTRLPAHATVLGRILLQDLSLGELR
DLYPEEHLESYSPNTPRTVLELFNLLQSDRLRGFVQGEGFFESTISTVAAPVRDHSGKVVAAMGATIPSGHIEPNSIDNL
VSTVRASADQLSHLLNYAPDSHDNVTSIFRSKQHESV
Download Length: 834 bp
>AT29532 NC_021499:1668785-1669618 [Pseudomonas resinovorans NBRC 106553]
ATGGATAAGCCAGACGATCCGCAAGACAAGTACATAGTGCCCGGCCTGGAGCGCGGCCTGCTGCTGCTCTGCGAGTTCAG
CCGGAAGAACCGTACCCTGTCGGCACCGGAGCTGGCGCGGCGCCTGAAGCTGCCGCGCTCGACCATCTTCCGCCTGCTGA
CCACCCTGGAAACCATGGGCTTCGTCACCCGCAACGGCAACGAGTACCGCCTGGGCATGGCGGTGCTGCGTCTGGGCTTC
GAGTACCTGGCCTCGCTGGAACTGACCGAACTCGGCCAGCCGCTGCTGAACCAGCTGTGCGACGACATCCGCTACCCCTG
CAACCTGGTGGTACGCGATGGCCGCTCCATCGTCTACGTGGCCAAGGTCTCGCCCTCCACCTTGCTGACCAGCACGGTCA
ACGTCGGCACCCGCCTGCCGGCCCACGCCACCGTGCTCGGCCGCATCCTCCTGCAGGACCTGTCGCTGGGCGAGCTGCGC
GACCTGTACCCGGAAGAACACCTGGAAAGCTACTCGCCGAACACCCCGCGTACCGTGCTGGAGCTGTTCAACCTGCTGCA
GAGCGATCGCCTGCGCGGCTTCGTCCAGGGCGAGGGCTTCTTCGAGTCGACCATCTCCACCGTGGCCGCGCCGGTGCGCG
ACCACAGCGGCAAGGTGGTGGCCGCCATGGGCGCCACCATCCCCTCGGGGCACATCGAGCCGAACAGCATCGACAACCTG
GTGAGCACCGTGCGCGCCAGCGCCGACCAGCTGTCGCACCTGCTCAACTACGCCCCGGACAGCCACGACAACGTCACCTC
CATCTTCCGGAGCAAGCAGCATGAGTCTGTGTGA
ATGGATAAGCCAGACGATCCGCAAGACAAGTACATAGTGCCCGGCCTGGAGCGCGGCCTGCTGCTGCTCTGCGAGTTCAG
CCGGAAGAACCGTACCCTGTCGGCACCGGAGCTGGCGCGGCGCCTGAAGCTGCCGCGCTCGACCATCTTCCGCCTGCTGA
CCACCCTGGAAACCATGGGCTTCGTCACCCGCAACGGCAACGAGTACCGCCTGGGCATGGCGGTGCTGCGTCTGGGCTTC
GAGTACCTGGCCTCGCTGGAACTGACCGAACTCGGCCAGCCGCTGCTGAACCAGCTGTGCGACGACATCCGCTACCCCTG
CAACCTGGTGGTACGCGATGGCCGCTCCATCGTCTACGTGGCCAAGGTCTCGCCCTCCACCTTGCTGACCAGCACGGTCA
ACGTCGGCACCCGCCTGCCGGCCCACGCCACCGTGCTCGGCCGCATCCTCCTGCAGGACCTGTCGCTGGGCGAGCTGCGC
GACCTGTACCCGGAAGAACACCTGGAAAGCTACTCGCCGAACACCCCGCGTACCGTGCTGGAGCTGTTCAACCTGCTGCA
GAGCGATCGCCTGCGCGGCTTCGTCCAGGGCGAGGGCTTCTTCGAGTCGACCATCTCCACCGTGGCCGCGCCGGTGCGCG
ACCACAGCGGCAAGGTGGTGGCCGCCATGGGCGCCACCATCCCCTCGGGGCACATCGAGCCGAACAGCATCGACAACCTG
GTGAGCACCGTGCGCGCCAGCGCCGACCAGCTGTCGCACCTGCTCAACTACGCCCCGGACAGCCACGACAACGTCACCTC
CATCTTCCGGAGCAAGCAGCATGAGTCTGTGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|