Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /Acetyltransf_4(toxin) |
| Location | 1343747..1345161 | Replicon | |
| Accession | NC_021499 | ||
| Organism | Pseudomonas resinovorans NBRC 106553 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | S6AN46 |
| Locus tag | PCA10_RS06200 | Protein ID | WP_016491185.1 |
| Coordinates | 1343747..1344316 (+) | Length | 190 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | PCA10_RS06205 | Protein ID | WP_041770548.1 |
| Coordinates | 1344322..1345161 (+) | Length | 280 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PCA10_RS06190 | 1339409..1339828 | + | 420 | WP_041770547.1 | hypothetical protein | - |
| PCA10_RS06195 | 1340027..1343506 | - | 3480 | WP_016491184.1 | hybrid sensor histidine kinase/response regulator | - |
| PCA10_RS06200 | 1343747..1344316 | + | 570 | WP_016491185.1 | GNAT family N-acetyltransferase | Toxin |
| PCA10_RS06205 | 1344322..1345161 | + | 840 | WP_041770548.1 | AraC family transcriptional regulator | Antitoxin |
| PCA10_RS06210 | 1345198..1345911 | + | 714 | WP_016491187.1 | AzlC family ABC transporter permease | - |
| PCA10_RS06215 | 1345911..1346240 | + | 330 | WP_016491188.1 | AzlD domain-containing protein | - |
| PCA10_RS06220 | 1346478..1348352 | + | 1875 | WP_016491189.1 | MFS transporter | - |
| PCA10_RS06225 | 1348392..1348709 | - | 318 | WP_016491190.1 | quaternary ammonium compound efflux SMR transporter SugE | - |
| PCA10_RS06230 | 1348857..1349798 | - | 942 | WP_016491191.1 | bile acid:sodium symporter family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 190 a.a. Molecular weight: 21136.16 Da Isoelectric Point: 9.5005
>T29531 WP_016491185.1 NC_021499:1343747-1344316 [Pseudomonas resinovorans NBRC 106553]
MFNPQPVTLQRGALRLDPLAESDIPALVTLAEANREALVYMNGPLRPDWYRQGLAAQREGQAVVFAIRLGDNLVGTTRFA
DFIPNLPAAEIGWTWLAAGEHGSGLNASIKYLMLRHAFEEWQLVRVQLKTAASNLRAQRAIEKLGAHREGVLRNHRRLAG
GRLDDSVLYSITDRDWPDVKQRLEALFSA
MFNPQPVTLQRGALRLDPLAESDIPALVTLAEANREALVYMNGPLRPDWYRQGLAAQREGQAVVFAIRLGDNLVGTTRFA
DFIPNLPAAEIGWTWLAAGEHGSGLNASIKYLMLRHAFEEWQLVRVQLKTAASNLRAQRAIEKLGAHREGVLRNHRRLAG
GRLDDSVLYSITDRDWPDVKQRLEALFSA
Download Length: 570 bp
>T29531 NC_021499:1343747-1344316 [Pseudomonas resinovorans NBRC 106553]
ATGTTCAATCCACAACCGGTCACCCTGCAGCGTGGCGCCTTGCGCCTCGATCCGCTGGCCGAGTCCGATATCCCGGCGCT
GGTCACCCTGGCCGAGGCCAACCGCGAAGCACTGGTGTACATGAACGGCCCCCTGCGCCCCGACTGGTATCGCCAGGGCC
TGGCTGCCCAGCGCGAAGGCCAGGCGGTGGTCTTCGCCATCCGTCTTGGCGACAACCTGGTGGGTACCACCCGCTTTGCC
GACTTCATCCCCAACCTGCCCGCCGCCGAGATCGGCTGGACCTGGCTCGCCGCTGGCGAGCACGGTAGCGGCCTGAATGC
CTCGATCAAGTACCTGATGCTGCGCCACGCCTTCGAGGAGTGGCAGCTGGTGCGGGTGCAACTGAAGACCGCCGCCAGCA
ACCTGCGCGCCCAGCGCGCCATCGAAAAGCTCGGCGCTCATCGCGAGGGCGTGCTGCGCAACCACCGCCGCCTGGCCGGC
GGGCGCCTGGACGACAGCGTGCTCTACAGCATCACCGACCGCGACTGGCCGGATGTGAAGCAACGCCTGGAGGCGCTGTT
CAGCGCTTGA
ATGTTCAATCCACAACCGGTCACCCTGCAGCGTGGCGCCTTGCGCCTCGATCCGCTGGCCGAGTCCGATATCCCGGCGCT
GGTCACCCTGGCCGAGGCCAACCGCGAAGCACTGGTGTACATGAACGGCCCCCTGCGCCCCGACTGGTATCGCCAGGGCC
TGGCTGCCCAGCGCGAAGGCCAGGCGGTGGTCTTCGCCATCCGTCTTGGCGACAACCTGGTGGGTACCACCCGCTTTGCC
GACTTCATCCCCAACCTGCCCGCCGCCGAGATCGGCTGGACCTGGCTCGCCGCTGGCGAGCACGGTAGCGGCCTGAATGC
CTCGATCAAGTACCTGATGCTGCGCCACGCCTTCGAGGAGTGGCAGCTGGTGCGGGTGCAACTGAAGACCGCCGCCAGCA
ACCTGCGCGCCCAGCGCGCCATCGAAAAGCTCGGCGCTCATCGCGAGGGCGTGCTGCGCAACCACCGCCGCCTGGCCGGC
GGGCGCCTGGACGACAGCGTGCTCTACAGCATCACCGACCGCGACTGGCCGGATGTGAAGCAACGCCTGGAGGCGCTGTT
CAGCGCTTGA
Antitoxin
Download Length: 280 a.a. Molecular weight: 31120.27 Da Isoelectric Point: 7.0490
>AT29531 WP_041770548.1 NC_021499:1344322-1345161 [Pseudomonas resinovorans NBRC 106553]
MANGETTRFWQANELGGVELLHARYIEQRFAPHVHEGYVFTVIESGAQRFRHRGSDHLAPVGSMVLINPDELHTGSKAHE
QGWRYRGFYPDLERVSEVLEELDIPMDGLPGFAESVIHDPEVAATFINLHRMLESSSPALQVQEAWREAILLLFRRHARI
AMPRAAGSEPRAVALAREILSAHLAEPPSLEDLAAEVGLSAFHFARTFRHATGMPPYAWLKQRRLEQARALLKAGCAPAG
VAAQLGFSDQSHLTRQFKQAYGVGPGEYRDACARSFKTH
MANGETTRFWQANELGGVELLHARYIEQRFAPHVHEGYVFTVIESGAQRFRHRGSDHLAPVGSMVLINPDELHTGSKAHE
QGWRYRGFYPDLERVSEVLEELDIPMDGLPGFAESVIHDPEVAATFINLHRMLESSSPALQVQEAWREAILLLFRRHARI
AMPRAAGSEPRAVALAREILSAHLAEPPSLEDLAAEVGLSAFHFARTFRHATGMPPYAWLKQRRLEQARALLKAGCAPAG
VAAQLGFSDQSHLTRQFKQAYGVGPGEYRDACARSFKTH
Download Length: 840 bp
>AT29531 NC_021499:1344322-1345161 [Pseudomonas resinovorans NBRC 106553]
ATGGCGAACGGCGAGACGACGCGTTTCTGGCAGGCCAACGAGCTGGGTGGTGTGGAGTTGTTGCATGCGCGCTACATCGA
GCAACGCTTCGCACCCCATGTGCACGAGGGGTATGTGTTCACCGTGATAGAGTCCGGTGCGCAGCGATTCCGTCATCGGG
GCAGCGACCACCTGGCGCCGGTGGGCAGCATGGTGCTGATCAATCCCGACGAGTTGCACACCGGCTCCAAGGCCCATGAG
CAGGGCTGGCGCTACCGGGGCTTCTACCCCGACCTGGAACGGGTCAGCGAGGTGCTGGAGGAGCTGGATATTCCCATGGA
CGGCCTGCCGGGCTTCGCCGAGAGCGTGATCCATGATCCCGAGGTAGCGGCCACCTTCATCAACCTGCACCGGATGCTGG
AGAGCAGCTCGCCGGCGCTGCAGGTCCAGGAGGCCTGGCGCGAGGCGATCCTGCTGCTGTTCCGCCGCCATGCGCGCATC
GCCATGCCCCGTGCGGCCGGCTCCGAGCCTCGGGCGGTGGCGCTGGCGCGGGAGATTCTCAGCGCCCACCTGGCCGAGCC
GCCGTCCCTGGAGGACCTGGCCGCCGAGGTGGGGCTGTCGGCCTTCCATTTCGCCCGGACCTTCCGCCATGCCACCGGCA
TGCCGCCCTACGCCTGGCTCAAGCAGCGCCGCCTGGAACAGGCCCGCGCCCTGCTCAAGGCCGGCTGCGCGCCGGCCGGG
GTGGCGGCGCAGCTGGGGTTTTCCGACCAGAGCCACCTGACCCGCCAGTTCAAGCAAGCCTACGGCGTGGGGCCGGGCGA
GTACCGCGACGCCTGCGCAAGATCGTTCAAGACCCACTGA
ATGGCGAACGGCGAGACGACGCGTTTCTGGCAGGCCAACGAGCTGGGTGGTGTGGAGTTGTTGCATGCGCGCTACATCGA
GCAACGCTTCGCACCCCATGTGCACGAGGGGTATGTGTTCACCGTGATAGAGTCCGGTGCGCAGCGATTCCGTCATCGGG
GCAGCGACCACCTGGCGCCGGTGGGCAGCATGGTGCTGATCAATCCCGACGAGTTGCACACCGGCTCCAAGGCCCATGAG
CAGGGCTGGCGCTACCGGGGCTTCTACCCCGACCTGGAACGGGTCAGCGAGGTGCTGGAGGAGCTGGATATTCCCATGGA
CGGCCTGCCGGGCTTCGCCGAGAGCGTGATCCATGATCCCGAGGTAGCGGCCACCTTCATCAACCTGCACCGGATGCTGG
AGAGCAGCTCGCCGGCGCTGCAGGTCCAGGAGGCCTGGCGCGAGGCGATCCTGCTGCTGTTCCGCCGCCATGCGCGCATC
GCCATGCCCCGTGCGGCCGGCTCCGAGCCTCGGGCGGTGGCGCTGGCGCGGGAGATTCTCAGCGCCCACCTGGCCGAGCC
GCCGTCCCTGGAGGACCTGGCCGCCGAGGTGGGGCTGTCGGCCTTCCATTTCGCCCGGACCTTCCGCCATGCCACCGGCA
TGCCGCCCTACGCCTGGCTCAAGCAGCGCCGCCTGGAACAGGCCCGCGCCCTGCTCAAGGCCGGCTGCGCGCCGGCCGGG
GTGGCGGCGCAGCTGGGGTTTTCCGACCAGAGCCACCTGACCCGCCAGTTCAAGCAAGCCTACGGCGTGGGGCCGGGCGA
GTACCGCGACGCCTGCGCAAGATCGTTCAAGACCCACTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|