Detailed information of TA system TA029526

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): abiEi-abiEii/AbiEii-AbiEi
• Location: 1325105..1326537
• Replicon: chromosome
• Accession: NC_021485
• Organism: Streptococcus agalactiae 09mas018883

Toxin (Protein)

• Gene name: abiEi
• Uniprot ID: -
• Locus tag: BSA_RS06725
• Protein ID: WP_001030297.1
• Coordinates: 1325692..1326537 (+)
• Length: 282 a.a.

Antitoxin (Protein)

• Gene name: abiEii
• Uniprot ID: -
• Locus tag: BSA_RS06720
• Protein ID: WP_000037240.1
• Coordinates: 1325105..1325695 (+)
• Length: 197 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BSA_RS06720	1325105..1325695	+	591	WP_000037240.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	Antitoxin
BSA_RS06725	1325692..1326537	+	846	WP_001030297.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
BSA_RS06730	1326624..1329425	-	2802	WP_016480088.1	CHAP domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	lmb / scpB / scpB	1267312..1332336	65024

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (33-258)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (6-50)

Sequences

Toxin

Protein

• Length: 282 a.a.
• Molecular weight: 32486.15 Da
• Isoelectric Point: 5.0593

>T29526 WP_001030297.1 NC_021485:1325692-1326537 [Streptococcus agalactiae 09mas018883]
MNKAKLTALCHKISKNTGLTFNSVMTYYFLEVILKKLSQSSYSNHYIFKGGFLLSNVIGVESRSTVDIDFLFHQITLSEE
TVKQQLEEVLADSEKGISFTIQSITAIKESDDYGGYRATILCQLENIKQVIHLDIATGDVVTPQPITYDYKAIFDEDNFP
IIAYTIETILAEKLQTIYSRNFLNSRSKDFYDVYILSKLKKEDIDFIQLKNACQRTFSYRETELYFEKIIELLERFKSDP
IQNKQWQNYSKKYSYTKGISLADVLDEMISLITIIISTDLD

Nucleotide

• Length: 846 bp

>T29526 NC_021485:1325692-1326537 [Streptococcus agalactiae 09mas018883]
ATGAACAAAGCTAAATTAACAGCACTCTGTCATAAAATATCAAAGAATACTGGTTTAACCTTTAATTCCGTCATGACCTA
TTACTTCCTAGAAGTCATTTTGAAAAAATTAAGTCAAAGTTCTTATTCAAATCACTATATCTTCAAAGGAGGATTCCTAC
TTTCGAATGTCATCGGAGTTGAATCTCGTAGCACTGTTGATATTGACTTTTTATTCCATCAAATAACACTCTCAGAAGAA
ACTGTTAAACAGCAACTTGAAGAAGTTTTAGCAGATTCTGAAAAAGGTATTTCTTTCACAATTCAATCTATCACAGCTAT
AAAAGAAAGTGATGACTATGGTGGCTATCGTGCAACCATTTTGTGCCAACTTGAGAATATTAAACAAGTTATCCATTTGG
ATATTGCGACAGGTGATGTTGTAACTCCTCAGCCGATTACATACGACTATAAAGCTATTTTTGATGAAGACAATTTTCCA
ATCATTGCTTATACAATTGAAACAATTCTAGCTGAGAAACTTCAAACCATCTATTCACGCAACTTCTTGAACAGCAGAAG
CAAAGATTTTTACGATGTTTATATTCTTTCAAAACTGAAGAAAGAAGACATTGACTTCATTCAATTGAAAAATGCCTGTC
AGAGAACATTTTCATATCGCGAAACAGAACTCTATTTTGAAAAGATTATTGAACTACTCGAAAGGTTCAAATCTGACCCT
ATTCAGAATAAACAATGGCAAAATTATTCAAAAAAATATAGCTATACAAAGGGGATTTCACTTGCAGATGTTCTTGATGA
GATGATTAGTCTTATTACAATTATTATTTCTACAGACTTAGATTAA

Antitoxin

Protein

• Length: 197 a.a.
• Molecular weight: 23064.59 Da
• Isoelectric Point: 7.8056

>AT29526 WP_000037240.1 NC_021485:1325105-1325695 [Streptococcus agalactiae 09mas018883]
MSKKEILLDFIEKNNGIVTNKDCKALGIPTIYLTRLEKEGIIFRVEKGIFLTQNGDYDEYYFFQYRFPKAIFSYISALYL
QQFTDEIPQYFDVTVPRGYRFNTPPANLNIHFVSKEYSELGMTTVPTPMGNNVRVYDFERIICDFVIHREKIDSELFVKT
LQSYGNYSKKNLAKLYEYATKMNTLEKVKQTLEVLI

Nucleotide

• Length: 591 bp

>AT29526 NC_021485:1325105-1325695 [Streptococcus agalactiae 09mas018883]
ATGTCAAAAAAAGAGATTCTACTCGATTTTATAGAAAAGAACAATGGCATTGTAACAAACAAAGATTGTAAAGCACTAGG
TATTCCAACAATATATCTGACAAGACTAGAGAAAGAAGGCATTATCTTCCGAGTTGAAAAAGGTATTTTCCTAACCCAAA
ACGGAGACTATGATGAATACTACTTCTTTCAATATCGTTTTCCTAAGGCTATTTTCTCTTATATTTCGGCACTGTATCTA
CAACAGTTTACAGATGAAATTCCACAATATTTTGATGTGACAGTTCCTAGAGGCTACCGCTTTAATACTCCTCCAGCTAA
TCTAAATATTCACTTTGTCTCTAAAGAATACAGCGAGCTGGGAATGACTACTGTACCTACTCCTATGGGAAACAACGTAA
GGGTATATGATTTTGAACGTATTATTTGTGATTTTGTAATACATCGAGAAAAGATTGATTCCGAACTCTTTGTCAAGACA
CTTCAATCTTATGGGAACTATTCTAAAAAAAATCTAGCAAAACTCTATGAATATGCGACAAAAATGAATACTTTAGAAAA
AGTTAAACAAACTCTGGAGGTTCTAATATGA