29512

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 1733203..1734479 Replicon chromosome
Accession NC_021286
Organism Idiomarina loihiensis GSL 199

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag K734_RS13600 Protein ID WP_081423225.1
Coordinates 1733203..1733412 (+) Length 70 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID Q5R0V9
Locus tag K734_RS08255 Protein ID WP_011234857.1
Coordinates 1733412..1734479 (+) Length 356 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K734_RS08235 1728769..1731501 + 2733 WP_011234853.1 DUF2726 domain-containing protein -
K734_RS08240 1731546..1732073 + 528 WP_011234854.1 DUF4433 domain-containing protein -
K734_RS08250 1732039..1733180 + 1142 WP_166649024.1 IS3 family transposase -
K734_RS13600 1733203..1733412 + 210 WP_081423225.1 DUF4433 domain-containing protein Toxin
K734_RS08255 1733412..1734479 + 1068 WP_011234857.1 macro domain-containing protein Antitoxin
K734_RS08260 1734671..1734934 + 264 Protein_1627 type I restriction-modification system subunit M N-terminal domain-containing protein -
K734_RS08265 1734999..1736003 + 1005 WP_011234858.1 SEC-C domain-containing protein -
K734_RS08270 1736177..1736692 + 516 WP_011234859.1 hypothetical protein -
K734_RS08275 1736692..1737495 + 804 WP_011234860.1 DUF3037 domain-containing protein -
K734_RS08280 1737740..1738537 - 798 WP_011234861.1 dioxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1725303..1743414 18111


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(1-69)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 70 a.a.        Molecular weight: 8399.67 Da        Isoelectric Point: 9.8196

>T29512 WP_081423225.1 NC_021286:1733203-1733412 [Idiomarina loihiensis GSL 199]
IQRRDFKRDFNDLGKLDRYQAEALIHRHFPITLLKGIVCYDEKVKQFIEQKVGNYGQNIKVINRPDWYF

Download         Length: 210 bp

>T29512 NC_021286:1733203-1733412 [Idiomarina loihiensis GSL 199]
ATCCAACGGCGTGACTTTAAACGTGACTTCAATGACTTAGGCAAGCTCGATAGATACCAGGCAGAGGCTTTAATCCACCG
TCACTTCCCTATTACACTTTTAAAAGGTATTGTGTGTTATGACGAAAAAGTAAAACAATTTATCGAACAAAAAGTCGGTA
ACTACGGTCAAAATATAAAAGTCATAAACCGCCCAGATTGGTACTTTTGA

Antitoxin


Download         Length: 356 a.a.        Molecular weight: 40165.03 Da        Isoelectric Point: 6.0669

>AT29512 WP_011234857.1 NC_021286:1733412-1734479 [Idiomarina loihiensis GSL 199]
MLNYKTGNLLESEAEALVNTVNTVGVMGKGIALMFKERFPANMEAYSQACKENKVKTGKMFVTHTNELVNPQWIVNFPTK
QHWRAKSKIEWIEEGLKDLRAFIIDNNIRSIAIPPLGAGNGGLDWDNVLPLIQKHLGDMTDIDIQIYQPTQQYQNVSKQS
GVEQLTAARAMIAELIRRYWVLGNECTLLEVQKLAWFLQRAIQQEGKESPLRLTFQPRNYGPYASDLTHLLNRLDGSYLQ
SDKRIPDAKATDVIAFNDNKRETVAAFLQAEATEFQYALDKATEIIEGFESPFGLELLATVDWLMTEGNVNPDADSVIEA
LTYWPAGAKWAQRKLNMFDKKAISIAITALMRKLH

Download         Length: 1068 bp

>AT29512 NC_021286:1733412-1734479 [Idiomarina loihiensis GSL 199]
ATGCTCAATTATAAGACAGGCAATTTATTAGAATCTGAAGCTGAAGCCCTTGTTAATACCGTAAATACCGTCGGTGTTAT
GGGTAAAGGGATCGCTTTGATGTTTAAAGAAAGGTTTCCTGCAAATATGGAAGCCTATTCTCAGGCCTGTAAAGAGAATA
AAGTGAAGACAGGCAAAATGTTCGTTACTCACACCAACGAACTGGTCAACCCTCAATGGATCGTGAACTTTCCGACAAAG
CAACATTGGCGTGCCAAATCAAAAATAGAATGGATTGAAGAAGGGTTAAAAGATTTAAGAGCTTTCATTATTGATAATAA
CATTCGCTCAATTGCTATCCCTCCTCTAGGAGCAGGCAATGGTGGCTTAGACTGGGATAACGTTCTTCCCCTGATACAAA
AGCATCTGGGCGATATGACTGACATCGATATTCAAATTTATCAGCCTACGCAGCAGTACCAAAACGTCAGCAAACAATCT
GGAGTTGAGCAACTAACAGCTGCTCGAGCAATGATTGCAGAGCTGATAAGACGTTACTGGGTATTAGGTAATGAATGTAC
CCTACTTGAGGTGCAAAAGCTTGCATGGTTCCTGCAACGAGCCATACAGCAAGAAGGGAAAGAGAGCCCACTTAGACTGA
CCTTTCAGCCCAGAAATTACGGACCCTATGCCAGTGACTTAACGCACTTATTAAATCGATTAGATGGCAGCTATTTACAG
TCGGACAAGCGTATTCCCGACGCAAAAGCGACAGATGTGATTGCCTTTAATGATAATAAGCGGGAAACCGTTGCAGCTTT
CCTACAAGCCGAAGCAACTGAGTTTCAATATGCATTGGACAAAGCGACAGAAATTATTGAAGGGTTCGAATCTCCCTTTG
GACTCGAGCTGCTCGCGACAGTTGACTGGCTGATGACTGAGGGGAACGTAAATCCAGACGCGGATAGTGTAATAGAAGCA
TTAACCTATTGGCCTGCTGGTGCTAAATGGGCGCAGCGCAAACTAAATATGTTTGATAAAAAGGCCATCTCAATTGCTAT
CACCGCATTAATGAGAAAGCTGCACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB Q5R0V9

References