Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1240620..1241151 Replicon chromosome
Accession NC_021286
Organism Idiomarina loihiensis GSL 199

Toxin (Protein)


Gene name relE Uniprot ID Q5QYX2
Locus tag K734_RS05930 Protein ID WP_011234412.1
Coordinates 1240620..1240907 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q5QTT1
Locus tag K734_RS05935 Protein ID WP_011234413.1
Coordinates 1240897..1241151 (-) Length 85 a.a.

Genomic Context

K734_RS05945K734_RS05950K734_RS05955K734_RS05915K734_RS05920K734_RS05925K734_RS05930K734_RS05935K734_RS05940
Location: 1243747..1244670 (924 bp)
Type: Others
Protein ID: WP_011234415.1
Location: 1244812..1245351 (540 bp)
Type: Others
Protein ID: WP_011234416.1
Location: 1245403..1245801 (399 bp)
Type: Others
Protein ID: WP_011234417.1
Location: 1235755..1237374 (1620 bp)
Type: Others
Protein ID: WP_011234409.1
Location: 1237353..1238420 (1068 bp)
Type: Others
Protein ID: WP_011234410.1
Location: 1238422..1240614 (2193 bp)
Type: Others
Protein ID: WP_011234411.1
Location: 1240620..1240907 (288 bp)
Type: Toxin
Protein ID: WP_011234412.1
Location: 1240897..1241151 (255 bp)
Type: Antitoxin
Protein ID: WP_011234413.1
Location: 1241214..1243538 (2325 bp)
Type: Others
Protein ID: WP_011234414.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
K734_RS059151235755..1237374-1620WP_011234409.1ABC transporter permease subunit-
K734_RS059201237353..1238420-1068WP_011234410.1ABC transporter substrate-binding protein-
K734_RS059251238422..1240614-2193WP_011234411.1bifunctional TVP38/TMEM64 family protein/FAD-dependent oxidoreductase-
K734_RS059301240620..1240907-288WP_011234412.1type II toxin-antitoxin system RelE/ParE family toxinToxin
K734_RS059351240897..1241151-255WP_011234413.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
K734_RS059401241214..1243538-2325WP_011234414.1TonB-dependent receptor-
K734_RS059451243747..1244670+924WP_011234415.1AraC family transcriptional regulator-
K734_RS059501244812..1245351+540WP_011234416.1carboxymuconolactone decarboxylase family protein-
K734_RS059551245403..1245801+399WP_011234417.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(12-74)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11276.32 Da        Isoelectric Point: 11.0167

>T29510 WP_011234412.1 NC_021286:c1240907-1240620 [Idiomarina loihiensis GSL 199]
MSYKLTFKRSAYKEWKKLNKDVQAQFKARLKQRLESPHVPASRLKGMDNCYKVKLRKLGYRLVYQVRDSELVVTVVALGK
RDKNRVYISAQKRLD

Download         Length: 288 bp

>T29510 NC_021286:c1240907-1240620 [Idiomarina loihiensis GSL 199]
ATGAGTTATAAGCTGACGTTTAAACGTTCAGCTTATAAAGAATGGAAAAAGTTGAACAAGGATGTTCAGGCGCAATTTAA
AGCCAGACTCAAGCAGAGGCTTGAATCACCTCATGTCCCGGCGTCTCGCTTAAAGGGAATGGATAACTGTTACAAAGTGA
AATTGCGAAAACTGGGTTATAGATTGGTTTATCAAGTAAGAGATTCCGAGCTTGTGGTTACGGTTGTAGCTTTAGGCAAA
CGTGATAAAAACAGAGTGTATATTAGCGCTCAGAAACGACTGGATTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9655.95 Da        Isoelectric Point: 4.4498

>AT29510 WP_011234413.1 NC_021286:c1241151-1240897 [Idiomarina loihiensis GSL 199]
MKTVRPIYARNSTSISELKKNPMAVVEESHGEPVAVLNRNQPAFYCIPAATYEALMEELEDRDLLELVKKRQHEDEVEVN
IDEL

Download         Length: 255 bp

>AT29510 NC_021286:c1241151-1240897 [Idiomarina loihiensis GSL 199]
ATGAAAACGGTTAGACCCATTTATGCACGCAACTCAACTAGCATTAGTGAGTTGAAAAAGAACCCAATGGCGGTTGTTGA
AGAGAGTCACGGTGAGCCGGTGGCTGTACTGAATCGGAATCAGCCCGCATTTTATTGCATTCCGGCAGCAACCTATGAAG
CGTTGATGGAAGAGCTGGAAGATAGGGATTTACTGGAGTTAGTTAAAAAACGCCAGCATGAAGATGAAGTCGAGGTGAAC
ATCGATGAGTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBQ5QYX2

Antitoxin

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Source
ID
Structure
AlphaFold DBQ5QTT1

References