Detailed information of TA system TA029510

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 1240620..1241151
• Replicon: chromosome
• Accession: NC_021286
• Organism: Idiomarina loihiensis GSL 199

Toxin (Protein)

• Gene name: relE
• Uniprot ID: Q5QYX2
• Locus tag: K734_RS05930
• Protein ID: WP_011234412.1
• Coordinates: 1240620..1240907 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: Q5QTT1
• Locus tag: K734_RS05935
• Protein ID: WP_011234413.1
• Coordinates: 1240897..1241151 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
K734_RS05915	1235755..1237374	-	1620	WP_011234409.1	ABC transporter permease subunit	-
K734_RS05920	1237353..1238420	-	1068	WP_011234410.1	ABC transporter substrate-binding protein	-
K734_RS05925	1238422..1240614	-	2193	WP_011234411.1	bifunctional TVP38/TMEM64 family protein/FAD-dependent oxidoreductase	-
K734_RS05930	1240620..1240907	-	288	WP_011234412.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
K734_RS05935	1240897..1241151	-	255	WP_011234413.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
K734_RS05940	1241214..1243538	-	2325	WP_011234414.1	TonB-dependent receptor	-
K734_RS05945	1243747..1244670	+	924	WP_011234415.1	AraC family transcriptional regulator	-
K734_RS05950	1244812..1245351	+	540	WP_011234416.1	carboxymuconolactone decarboxylase family protein	-
K734_RS05955	1245403..1245801	+	399	WP_011234417.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (12-74)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11276.32 Da
• Isoelectric Point: 11.0167

>T29510 WP_011234412.1 NC_021286:c1240907-1240620 [Idiomarina loihiensis GSL 199]
MSYKLTFKRSAYKEWKKLNKDVQAQFKARLKQRLESPHVPASRLKGMDNCYKVKLRKLGYRLVYQVRDSELVVTVVALGK
RDKNRVYISAQKRLD

Nucleotide

• Length: 288 bp

>T29510 NC_021286:c1240907-1240620 [Idiomarina loihiensis GSL 199]
ATGAGTTATAAGCTGACGTTTAAACGTTCAGCTTATAAAGAATGGAAAAAGTTGAACAAGGATGTTCAGGCGCAATTTAA
AGCCAGACTCAAGCAGAGGCTTGAATCACCTCATGTCCCGGCGTCTCGCTTAAAGGGAATGGATAACTGTTACAAAGTGA
AATTGCGAAAACTGGGTTATAGATTGGTTTATCAAGTAAGAGATTCCGAGCTTGTGGTTACGGTTGTAGCTTTAGGCAAA
CGTGATAAAAACAGAGTGTATATTAGCGCTCAGAAACGACTGGATTAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9655.95 Da
• Isoelectric Point: 4.4498

>AT29510 WP_011234413.1 NC_021286:c1241151-1240897 [Idiomarina loihiensis GSL 199]
MKTVRPIYARNSTSISELKKNPMAVVEESHGEPVAVLNRNQPAFYCIPAATYEALMEELEDRDLLELVKKRQHEDEVEVN
IDEL

Nucleotide

• Length: 255 bp

>AT29510 NC_021286:c1241151-1240897 [Idiomarina loihiensis GSL 199]
ATGAAAACGGTTAGACCCATTTATGCACGCAACTCAACTAGCATTAGTGAGTTGAAAAAGAACCCAATGGCGGTTGTTGA
AGAGAGTCACGGTGAGCCGGTGGCTGTACTGAATCGGAATCAGCCCGCATTTTATTGCATTCCGGCAGCAACCTATGAAG
CGTTGATGGAAGAGCTGGAAGATAGGGATTTACTGGAGTTAGTTAAAAAACGCCAGCATGAAGATGAAGTCGAGGTGAAC
ATCGATGAGTTATAA

Structures

Toxin

• AlphaFold DB: Q5QYX2

Antitoxin

• AlphaFold DB: Q5QTT1