Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 300927..301437 Replicon chromosome
Accession NC_021286
Organism Idiomarina loihiensis GSL 199

Toxin (Protein)


Gene name relB Uniprot ID Q5R151
Locus tag K734_RS01430 Protein ID WP_011233548.1
Coordinates 301174..301437 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID Q5QUM2
Locus tag K734_RS01425 Protein ID WP_011233547.1
Coordinates 300927..301181 (+) Length 85 a.a.

Genomic Context

K734_RS01415K734_RS01425K734_RS01430K734_RS01435K734_RS01440K734_RS01445K734_RS01450K734_RS01460K734_RS01410K734_RS01420K734_RS01455
Location: 298650..298865 (216 bp)
Type: Others
Protein ID: WP_011233545.1
Location: 300927..301181 (255 bp)
Type: Antitoxin
Protein ID: WP_011233547.1
Location: 301174..301437 (264 bp)
Type: Toxin
Protein ID: WP_011233548.1
Location: 301633..302124 (492 bp)
Type: Others
Protein ID: WP_011233549.1
Location: 302235..302789 (555 bp)
Type: Others
Protein ID: WP_011233550.1
Location: 302845..303225 (381 bp)
Type: Others
Protein ID: WP_011233551.1
Location: 303276..303830 (555 bp)
Type: Others
Protein ID: WP_011233552.1
Location: 304856..305968 (1113 bp)
Type: Others
Protein ID: WP_011233554.1
Location: 297989..298468 (480 bp)
Type: Others
Protein ID: WP_011233544.1
Location: 299024..300652 (1629 bp)
Type: Others
Protein ID: WP_011233546.1
Location: 303914..304738 (825 bp)
Type: Others
Protein ID: WP_011233553.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
K734_RS01410297989..298468-480WP_011233544.1transcription elongation factor GreB-
K734_RS01415298650..298865+216WP_011233545.1TIGR02450 family Trp-rich protein-
K734_RS01420299024..300652-1629WP_011233546.1hypothetical protein-
K734_RS01425300927..301181+255WP_011233547.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
K734_RS01430301174..301437+264WP_011233548.1Txe/YoeB family addiction module toxinToxin
K734_RS01435301633..302124+492WP_011233549.1hypothetical protein-
K734_RS01440302235..302789+555WP_011233550.1hypothetical protein-
K734_RS01445302845..303225+381WP_011233551.1hypothetical protein-
K734_RS01450303276..303830+555WP_011233552.1YaeQ family protein-
K734_RS01455303914..304738-825WP_011233553.1hypothetical protein-
K734_RS01460304856..305968+1113WP_011233554.1DUF4241 domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10353.81 Da        Isoelectric Point: 9.7108

>T29509 WP_011233548.1 NC_021286:301174-301437 [Idiomarina loihiensis GSL 199]
MSKRLLSWTDEAWKDYLYWQTQDKKTLKRINRLVADVKRSPFEGIGKPEPLKENLAGFWSRRIDDTNRLVYAADDSAITI
ISCRYHY

Download         Length: 264 bp

>T29509 NC_021286:301174-301437 [Idiomarina loihiensis GSL 199]
ATGAGTAAGAGGTTGCTGTCATGGACTGATGAGGCCTGGAAAGACTATTTATATTGGCAGACTCAAGATAAAAAGACACT
TAAACGTATCAACAGATTAGTTGCCGATGTTAAAAGATCGCCGTTCGAAGGTATTGGTAAACCTGAGCCGTTAAAAGAAA
ACCTGGCGGGTTTCTGGTCGCGGCGAATCGATGATACGAATAGACTGGTATACGCAGCCGACGACAGTGCAATTACAATT
ATTTCTTGTCGTTATCACTACTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9496.75 Da        Isoelectric Point: 5.6993

>AT29509 WP_011233547.1 NC_021286:300927-301181 [Idiomarina loihiensis GSL 199]
MRIVSFTEARNGLKAVLDSVINDADTTVITRRDSEDAVVMSLDYYNSLMETVHLLRSPANAEHLNKSIAQYKEGKAKKRE
LLDE

Download         Length: 255 bp

>AT29509 NC_021286:300927-301181 [Idiomarina loihiensis GSL 199]
ATGAGAATAGTCTCTTTTACTGAAGCCCGAAATGGCTTAAAAGCAGTGTTGGACAGCGTAATCAACGATGCTGATACAAC
GGTTATTACCCGTCGTGACTCGGAAGATGCCGTGGTTATGTCTTTAGATTACTACAATAGCCTAATGGAAACGGTTCATT
TGCTCCGTTCGCCGGCAAATGCTGAGCATTTGAATAAATCTATTGCTCAATACAAAGAAGGGAAAGCCAAAAAGAGAGAG
TTATTAGATGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBQ5R151

Antitoxin

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Source
ID
Structure
AlphaFold DBQ5QUM2

References