295079

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 3572594..3573287 Replicon chromosome
Accession NZ_OW011623
Organism Thauera sp. PIV-1 strain Piv1

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag QM552_RS16580 Protein ID WP_282811068.1
Coordinates 3572594..3572971 (+) Length 126 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag QM552_RS16585 Protein ID WP_282811069.1
Coordinates 3572952..3573287 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QM552_RS16570 (C4PIVTH_3487) 3568870..3571818 - 2949 WP_282811066.1 Tn3 family transposase -
QM552_RS16575 (C4PIVTH_3488) 3571823..3572413 - 591 WP_282811067.1 recombinase family protein -
QM552_RS16580 (C4PIVTH_3489) 3572594..3572971 + 378 WP_282811068.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QM552_RS16585 (C4PIVTH_3490) 3572952..3573287 + 336 WP_282811069.1 helix-turn-helix transcriptional regulator Antitoxin
QM552_RS16590 (C4PIVTH_3491) 3573301..3573660 + 360 WP_282811070.1 transposase -
QM552_RS16595 (C4PIVTH_3492) 3573657..3573881 + 225 WP_282811071.1 hypothetical protein -
QM552_RS16600 3574075..3574227 + 153 WP_282811691.1 hypothetical protein -
QM552_RS16605 (C4PIVTH_3494) 3574506..3576110 - 1605 WP_282811072.1 IS66 family transposase -
QM552_RS16610 (C4PIVTH_3495) 3576207..3576545 - 339 WP_282811073.1 IS66 family insertion sequence element accessory protein TnpB -
QM552_RS16615 (C4PIVTH_3496) 3576545..3576877 - 333 WP_282811074.1 hypothetical protein -
QM552_RS16620 (C4PIVTH_3497) 3576955..3577818 + 864 Protein_3262 Tn3 family transposase -
QM552_RS16625 (C4PIVTH_3498) 3577855..3578166 + 312 Protein_3263 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside IScluster/Tn - - 3571823..3578202 6379


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(16-109)

Antitoxin

HigA2-like, helix-turn-helix domain

(18-97)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 13774.90 Da        Isoelectric Point: 8.8594

>T295079 WP_282811068.1 NZ_OW011623:3572594-3572971 [Thauera sp. PIV-1]
MVEKEKPLEWIASSYKDLMTLPPDVRRRFGYALSLAQMGDQDDAAKVLKGFGGAGVLEVVEDDAGGTYRAVYTVKFAEAV
FVLHCFQKKSKSGIATPKADMDIIRARLKVAEALAQELRNAKTNH

Download         Length: 378 bp

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12189.37 Da        Isoelectric Point: 10.5376

>AT295079 WP_282811069.1 NZ_OW011623:3572952-3573287 [Thauera sp. PIV-1]
MQKRIIEGVEVQRSSGNVFADLGLPDAEKLKIKTGLVVEIRKAMRTLGLTQQAAAKRMGIPQPKVSGMMRGDFTNLSERK
LMDCLNRLGYDIEIKVRPAAEPVGHLTLATA

Download         Length: 336 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References