Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 31567..32092 Replicon chromosome
Accession NZ_OW011623
Organism Thauera sp. PIV-1 strain Piv1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QM552_RS00155 Protein ID WP_282809120.1
Coordinates 31814..32092 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID N6XYE1
Locus tag QM552_RS00150 Protein ID WP_004292372.1
Coordinates 31567..31824 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QM552_RS00130 (C4PIVTH_0031) 27591..27860 + 270 WP_094269086.1 DUF4160 domain-containing protein -
QM552_RS00135 (C4PIVTH_0032) 27853..28101 + 249 WP_004292369.1 DUF2442 domain-containing protein -
QM552_RS00140 (C4PIVTH_0034) 28303..28878 - 576 WP_282809118.1 GrpB family protein -
QM552_RS00145 (C4PIVTH_0035) 29153..31405 + 2253 WP_282809119.1 flagellin -
QM552_RS00150 (C4PIVTH_0036) 31567..31824 + 258 WP_004292372.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
QM552_RS00155 (C4PIVTH_0037) 31814..32092 + 279 WP_282809120.1 Txe/YoeB family addiction module toxin Toxin
QM552_RS00160 (C4PIVTH_0038) 32244..34892 + 2649 WP_282809121.1 flagellin -
QM552_RS00165 (C4PIVTH_0039) 34977..35417 + 441 WP_282809122.1 flagellar protein FlaG -
QM552_RS00170 (C4PIVTH_0040) 35488..36864 + 1377 WP_282809123.1 flagellar filament capping protein FliD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 27853..56066 28213


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(12-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 11061.64 Da        Isoelectric Point: 7.2904

>T295075 WP_282809120.1 NZ_OW011623:31814-32092 [Thauera sp. PIV-1]
MPTEHRLLQLTWTLAAWEDYEYWQGQDRKTLKRINTLIKDCLRHPFEGIGKPEPLRENLSGFWSRRIDDAHRLVYCAEGE
SLIIIACRYHYQ

Download         Length: 279 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9552.70 Da        Isoelectric Point: 5.5721

>AT295075 WP_004292372.1 NZ_OW011623:31567-31824 [Thauera sp. PIV-1]
MRVVNFSEARNGLKHVIDQVVDDADYTVIARRDAPDAVLMSLDTFNSLMETVHLLKSPANAAHLARSIEQYRQGNTAQRE
LRDAD

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB N6XYE1

References