Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 290033..290564 Replicon chromosome
Accession NZ_OV996158
Organism Enterococcus mundtii strain P2005

Toxin (Protein)


Gene name relE Uniprot ID A0A2T5DGB3
Locus tag N7O26_RS01355 Protein ID WP_019722402.1
Coordinates 290292..290564 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2T5DG49
Locus tag N7O26_RS01350 Protein ID WP_019722403.1
Coordinates 290033..290299 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7O26_RS01330 285084..286613 + 1530 WP_086334310.1 cardiolipin synthase -
N7O26_RS01335 286874..288370 + 1497 WP_260697327.1 phytoene desaturase family protein -
N7O26_RS01340 288386..289465 + 1080 WP_081277432.1 glycosyltransferase family 2 protein -
N7O26_RS01345 289475..289966 + 492 WP_065096237.1 glycosyl-4,4'-diaponeurosporenoate acyltransferase -
N7O26_RS01350 290033..290299 + 267 WP_019722403.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
N7O26_RS01355 290292..290564 + 273 WP_019722402.1 type II toxin-antitoxin system YafQ family toxin Toxin
N7O26_RS01360 291102..291449 - 348 WP_260697328.1 hypothetical protein -
N7O26_RS01365 291412..292803 - 1392 WP_260697329.1 Y-family DNA polymerase -
N7O26_RS01370 293356..294375 + 1020 WP_019722398.1 3-deoxy-7-phosphoheptulonate synthase -
N7O26_RS01375 294390..295454 + 1065 WP_065096235.1 3-dehydroquinate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(9-84)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10603.43 Da        Isoelectric Point: 10.1735

>T295071 WP_019722402.1 NZ_OV996158:290292-290564 [Enterococcus mundtii]
MLDIFYTSQFKRDYKKAKKQGKDLAKLKKVLSLLQSQHKLPKVYRDHHLTGNYAGFRECHISPDWLLVYKIDTDQLLLIL
ARLGSHSELF

Download         Length: 273 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9744.12 Da        Isoelectric Point: 4.6533

>AT295071 WP_019722403.1 NZ_OV996158:290033-290299 [Enterococcus mundtii]
METTKKKPIHISIDEELKKDAEQLFDELGMNMTTAITVFLKQSVNKQAIPFKIEKGNPATLQALKDAKDGNIHGGFSSVD
ELLEDLDA

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2T5DGB3

Antitoxin

Source ID Structure
AlphaFold DB A0A2T5DG49

References