Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1945713..1945858 | Replicon | chromosome |
| Accession | NZ_OV754010 | ||
| Organism | Klebsiella pneumoniae isolate BB1541 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1945749..1945851 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1945713..1945858 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| O0V11_RS09485 (VKR_01887) | 1940843..1942903 | + | 2061 | WP_064145333.1 | oligopeptidase B | - |
| O0V11_RS09490 (VKR_01888) | 1942907..1943566 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| O0V11_RS09495 (VKR_01889) | 1943645..1943875 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| O0V11_RS09500 (VKR_01890) | 1943988..1944362 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| O0V11_RS09505 (VKR_01891) | 1944366..1945235 | + | 870 | WP_004189267.1 | copper homeostasis membrane protein CopD | - |
| O0V11_RS09510 (VKR_01892) | 1945252..1945590 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 1945713..1945858 | - | 146 | - | - | Antitoxin |
| - | 1945749..1945851 | + | 103 | - | - | Toxin |
| O0V11_RS09515 | 1946227..1946370 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| O0V11_RS09520 (VKR_01895) | 1946475..1947443 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| O0V11_RS09525 (VKR_01896) | 1947600..1948253 | + | 654 | WP_064145335.1 | protein-serine/threonine phosphatase | - |
| O0V11_RS09530 (VKR_01897) | 1948250..1948441 | - | 192 | WP_002911395.1 | YebW family protein | - |
| O0V11_RS09535 (VKR_01898) | 1948539..1948778 | - | 240 | WP_002911393.1 | YebV family protein | - |
| O0V11_RS09540 (VKR_01899) | 1948894..1950327 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T295056 NZ_OV754010:1945749-1945851 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT295056 NZ_OV754010:c1945858-1945713 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
