Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 801224..801881 Replicon chromosome
Accession NZ_OV753634
Organism Klebsiella quasipneumoniae isolate BB1501

Toxin (Protein)


Gene name cptA Uniprot ID A0A2A5MNX1
Locus tag OZE11_RS03945 Protein ID WP_004205323.1
Coordinates 801471..801881 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID W8UQ37
Locus tag OZE11_RS03940 Protein ID WP_002916312.1
Coordinates 801224..801490 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZE11_RS03915 (796433) 796433..797866 - 1434 WP_004205314.1 6-phospho-beta-glucosidase BglA -
OZE11_RS03920 (797985) 797985..798713 - 729 WP_004205316.1 MurR/RpiR family transcriptional regulator -
OZE11_RS03925 (798763) 798763..799074 + 312 WP_004205318.1 N(4)-acetylcytidine aminohydrolase -
OZE11_RS03930 (799237) 799237..799896 + 660 WP_004205319.1 hemolysin III family protein -
OZE11_RS03935 (799995) 799995..800978 - 984 WP_017899798.1 tRNA-modifying protein YgfZ -
OZE11_RS03940 (801224) 801224..801490 + 267 WP_002916312.1 FAD assembly factor SdhE Antitoxin
OZE11_RS03945 (801471) 801471..801881 + 411 WP_004205323.1 protein YgfX Toxin
OZE11_RS03950 (801888) 801888..802409 - 522 WP_004205324.1 flavodoxin FldB -
OZE11_RS03955 (802510) 802510..803406 + 897 WP_080936033.1 site-specific tyrosine recombinase XerD -
OZE11_RS03960 (803429) 803429..804142 + 714 WP_002916301.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
OZE11_RS03965 (804148) 804148..805881 + 1734 WP_004205327.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16035.83 Da        Isoelectric Point: 11.4778

>T295026 WP_004205323.1 NZ_OV753634:801471-801881 [Klebsiella quasipneumoniae]
VVLWQSDLRISWRAQWFSLLLHGVVAALVLLVPWPLSYTPIWLLLLSLVVFDCVRSQRRIHARRGEIKLLTDSRLRWQNA
DWEILGTPWVINSGMLLRLRHVDTRRGQHLWLAADSMDAGEWRDLRRLVLQKPAQE

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10480.98 Da        Isoelectric Point: 5.1116

>AT295026 WP_002916312.1 NZ_OV753634:801224-801490 [Klebsiella quasipneumoniae]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDTLSDADKQLFIRLLENDDPDLFNWLMNHGKPADAELQRMVTLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2A5MNX1

Antitoxin

Source ID Structure
AlphaFold DB A0A0H3GY41

References