Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2012372..2012517 Replicon chromosome
Accession NZ_OV408202
Organism Klebsiella pneumoniae isolate CNR146C9

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2012408..2012510 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2012372..2012517 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NBX86_RS09695 2007502..2009562 + 2061 WP_004148850.1 oligopeptidase B -
NBX86_RS09700 2009566..2010225 - 660 WP_032435029.1 exodeoxyribonuclease X -
NBX86_RS09705 2010304..2010534 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NBX86_RS09710 2010647..2011021 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NBX86_RS09715 2011025..2011894 + 870 WP_032435031.1 copper homeostasis membrane protein CopD -
NBX86_RS09720 2011911..2012249 + 339 WP_002911404.1 YebY family protein -
- 2012372..2012517 - 146 - - Antitoxin
- 2012408..2012510 + 103 - - Toxin
NBX86_RS09725 2012885..2013028 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NBX86_RS09730 2013133..2014101 - 969 WP_004151446.1 VirK/YbjX family protein -
NBX86_RS09735 2014258..2014911 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
NBX86_RS09740 2014908..2015099 - 192 WP_002911395.1 YebW family protein -
NBX86_RS09745 2015197..2015436 - 240 WP_002911393.1 YebV family protein -
NBX86_RS09750 2015552..2016985 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T295006 NZ_OV408202:2012408-2012510 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT295006 NZ_OV408202:c2012517-2012372 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References