Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-stbD/ParE-DnaT
Location 1512162..1512696 Replicon chromosome
Accession NZ_OV100759
Organism Aggregatibacter sp. Marseille-P9115

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LQ983_RS07255 Protein ID WP_111278766.1
Coordinates 1512162..1512452 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID -
Locus tag LQ983_RS07260 Protein ID WP_230622192.1
Coordinates 1512442..1512696 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ983_RS07220 1508322..1508633 - 312 WP_230622186.1 hypothetical protein -
LQ983_RS07225 1508630..1508803 - 174 WP_230622187.1 hypothetical protein -
LQ983_RS07230 1508817..1509826 - 1010 Protein_1385 site-specific integrase -
LQ983_RS07235 1509826..1510164 - 339 WP_230622188.1 hypothetical protein -
LQ983_RS07240 1510161..1510388 - 228 WP_230622189.1 host cell division inhibitor Icd-like protein -
LQ983_RS07245 1510876..1511100 - 225 WP_230622190.1 helix-turn-helix domain-containing protein -
LQ983_RS07250 1511213..1512127 - 915 WP_230622191.1 hypothetical protein -
LQ983_RS07255 1512162..1512452 - 291 WP_111278766.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LQ983_RS07260 1512442..1512696 - 255 WP_230622192.1 stability protein StbD Antitoxin
LQ983_RS07265 1512813..1513040 - 228 WP_230622193.1 hypothetical protein -
LQ983_RS07270 1513040..1513981 - 942 WP_230622194.1 P2 family phage major capsid protein -
LQ983_RS07275 1513993..1514688 - 696 WP_230622195.1 hypothetical protein -
LQ983_RS07280 1514685..1514912 - 228 WP_230622196.1 AlpA family transcriptional regulator -
LQ983_RS07285 1515565..1516572 - 1008 WP_230622630.1 tyrosine-type recombinase/integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1505212..1516578 11366


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11515.30 Da        Isoelectric Point: 10.4142

>T294996 WP_111278766.1 NZ_OV100759:c1512452-1512162 [Aggregatibacter sp. Marseille-P9115]
MTYKLTFDKRALKEWEKLGDTIRQQFKNKLAERLENPRVIGDKLRGYQNLYKIKLRSAGYRLVYEVNDNQIYILVLSVGK
RDRLDAYKNAEFRQAQ

Download         Length: 291 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9270.47 Da        Isoelectric Point: 4.1068

>AT294996 WP_230622192.1 NZ_OV100759:c1512696-1512442 [Aggregatibacter sp. Marseille-P9115]
MAIHHILTQQAASITDLKRDPMGIAQASQEGAVAILNRNQPAFYCVTPALFEYFQELAEDAELGRIAQERLSTLDPVEVS
LDDL

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References