294994

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 115983..116528 Replicon chromosome
Accession NZ_OV100759
Organism Aggregatibacter sp. Marseille-P9115

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LQ983_RS00535 Protein ID WP_111305671.1
Coordinates 116256..116528 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LQ983_RS00530 Protein ID WP_111305672.1
Coordinates 115983..116255 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ983_RS00515 111192..112562 - 1371 WP_230621253.1 TolC family protein -
LQ983_RS00520 112649..114580 - 1932 WP_230621254.1 MacB family efflux pump subunit -
LQ983_RS00525 114600..115775 - 1176 WP_230621255.1 efflux RND transporter periplasmic adaptor subunit -
LQ983_RS00530 115983..116255 + 273 WP_111305672.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LQ983_RS00535 116256..116528 + 273 WP_111305671.1 type II toxin-antitoxin system YafQ family toxin Toxin
LQ983_RS00540 116622..118292 + 1671 WP_230621256.1 glutamine--tRNA ligase -
LQ983_RS00545 118928..119263 + 336 WP_065286357.1 Imm8 family immunity protein -
LQ983_RS00550 119724..119945 + 222 WP_230621257.1 hypothetical protein -
LQ983_RS00555 120602..121045 - 444 WP_230621258.1 peptidoglycan-binding protein LysM -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-83)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10586.26 Da        Isoelectric Point: 9.5300

>T294994 WP_111305671.1 NZ_OV100759:116256-116528 [Aggregatibacter sp. Marseille-P9115]
MKISFTKDYKRDLKRLANQPEILLSAEMIDVMHHLLNGKNLPEKYKDHALSGNWKGFRDCHIKNDLVLIYHVNNEGLTLV
RLNTHSEVFR

Download         Length: 273 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10224.66 Da        Isoelectric Point: 4.5983

>AT294994 WP_111305672.1 NZ_OV100759:115983-116255 [Aggregatibacter sp. Marseille-P9115]
MTSYTFRLDPELKEQAFSVFRSYGLNPAQALKMILQQVVSTKSIPVQLDYQPNETTIRAMEDALSGKVESVETENVEELI
KKMQRVANEA

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References